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Slack / Private Message Drop, pp.459-460 [SLACK_000673] · slack_pm:msg:04773

Date: 2021-01-27 08:12
Type: chat message · slack
mentioned: Kristian G. Andersen
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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Oh and @Kristian Andersen correcting one mistake - THe cysteines in the sarbecos are very conserved but not 100%. RmYN02, (and noe the Thaibat and japan bat "deletes" or is missing a pair - Japan Bat essentially just excises the cysteine loop - of course it could will be the other way around with SC1 etc adding the new cysteine loop kinda like your "fake reinfection patient" just in the CTD instead of the NTD.

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2021-01-27 07:46 Robert F. Garry open

Here's the alignment file. [shared file(s): clustalo-E20210127-153037-0863-50955906-p2m.clustal_num]
2021-01-27 07:48 Robert F. Garry open

and the fasta files [shared file(s): betacovs fasta whole spike.docx]
2021-01-27 07:51 Robert F. Garry open

The indel structures of the the new asian bats are very interesting.
2021-01-27 08:04 Robert F. Garry open

I have a feeling that the other new bat covs will also fit in nicely....
2021-01-27 08:12 Robert F. Garry

Oh and @Kristian Andersen correcting one mistake - THe cysteines in the sarbecos are very conserved but not 100%. RmYN02, (and noe the Thaibat and japan bat "deletes" or is missing a pair - Japan Bat essentially just excises the cysteine loop - of course it could will be the other way around with SC1 etc adding the new cysteine loop kinda like your "fake reinfection patient" just in the CTD instead of the NTD.

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