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Slack / Private Message Drop, p.456 [SLACK_000670] · slack_pm:msg:04737

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Oh cool! It's really not much of a paper.

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-01-26 17:36 Edward C. Holmes open

Indeed! Sounds like an update is needed ASAP.
2021-01-26 17:44 Kristian G. Andersen open

I don't necessarily think it needs to get into people ASAP, but the whole process absolutely needs to be started ASAP - it's not a simple "six week and we're done" process. Better have this ready to go over the summer.
2021-01-26 17:46 Edward C. Holmes open

Totally agree.
2021-01-26 18:04 Kristian G. Andersen open

Just looking at that CamboBat paper - very interesting. One thing they miss - that mismatch in the key RBD residue where CamboBat has "P" and the PangoCoV and SC2 have "F" (and SC1 / RmYN02 have "L") the "pre"-SARS CoVs from e.g., civets ALSO have "P". Pretty interesting. [shared file(s): Screen Shot 2021-01-26 at 5.59.43PM.png, Screen Shot 2021-01-26 at 6.03.31 PM.png]
2021-01-26 18:09 Edward C. Holmes

Oh cool! It's really not much of a paper.
2021-01-26 18:14 Kristian G. Andersen open

No, it really isn't - more of a genome announcement (although, quite a genome!)
2021-01-26 18:16 Edward C. Holmes open

Yes, it's a beaut.
2021-01-26 18:19 Robert F. Garry open

They had lots of opportunities to really get into sarbecovirus evolution -they didn't.