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Slack / Private Message Drop, p.370 [SLACK_000584] · slack_pm:msg:03857

Page text: p.370 · original PDF

Date
2021-01-09 07:52
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Intelligence community assessments

Recipients on this medium are inferred from channel membership, not per-message addressing.

Ahhh yes - the Queen Victoria hotel is pretty special and you can take a side trip to the Ziika forest. Curious about Pooh, showing up in NIgeria (Christian Happi) and now Poor in Uganda. Not that many sequences from Africa, Something usual in Africans going on which I suspect relates to prior exposure to some yet uncharacterizedbetacornaviruses.

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Ahhh yes - the Queen Victoria hotel is pretty special and you can take a side trip to the Ziika forest. needs context speaker_own asserts

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  1. 2021-01-09 07:25 Andrew Rambaut open
    We have also seen an odd import (possibly from Uganda - but quite possibly with an intermediate location) that hasP681R so making the FCS RRRK - any thoughts on that? Interestingly it also has V367F & Q613H (but not614G - it is in lineage A). A small cluster, possibly growing.
  2. 2021-01-09 07:39 Robert F. Garry open
    Interesting - P681R would make the FCS RRRAR right? which is predicted to be a much better site than PRRAR but not as good as RRAR/KR. Q613H is pretty analogous to the lion mutation (from my virological christmas card) Q613R, both to a positive charge at pH >6.
  3. 2021-01-09 07:42 Andrew Rambaut open
    There are lions in Uganda.
  4. 2021-01-09 07:42 Andrew Rambaut open
    (so I have heard - I was supposed to be going there last year, sigh)
  5. 2021-01-09 07:52 Robert F. Garry
    Ahhh yes - the Queen Victoria hotel is pretty special and you can take a side trip to the Ziika forest. Curious about Pooh, showing up in NIgeria (Christian Happi) and now Poor in Uganda. Not that many sequences from Africa, Something usual in Africans going on which I suspect relates to prior exposure to some yet uncharacterizedbetacornaviruses.
  6. 2021-01-09 07:54 Robert F. Garry open
    Lot of immunosuppressed Africans, HIV and other causes, as well. So having the P681 changes may fit that meme.
  7. 2021-01-09 08:00 Andrew Rambaut open
    This is the new USA cluster with Eeek and Pooh: [shared file(s): image.png]
  8. 2021-01-09 08:11 Robert F. Garry open
    All in Maryland? Worth keeping an eye on it for sure...
  9. 2021-01-09 08:12 Andrew Rambaut open
    This one only has 484K but spans 4 months and 4 states: [shared file(s): image.png]

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