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Slack / Private Message Drop, p.328 [SLACK_000542] · slack_pm:msg:03448

Date: 2020-12-20 08:33
Type: chat message · slack
recipient: Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker: Robert F. Garry

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Note to self that the Benton structures are "stabilized" with two proline substitutions - this is what we did to ultimately get the Lassa GP structure.

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2020-12-20 07:59 Andrew Rambaut open

@Robert Garry I don't think 501Y turns up in mink.
2020-12-20 08:12 Robert F. Garry open

@Robert Garry It's N501T
2020-12-20 08:15 Robert F. Garry open

@Robert Garry Same residue changes to two diff amino acids when SC2 "adapts" to two diff animals.
2020-12-20 08:27 Robert F. Garry open

@Robert Garry In SC1 it's T501 fwiw.
2020-12-20 08:33 Robert F. Garry

Note to self that the Benton structures are "stabilized" with two proline substitutions - this is what we did to ultimately get the Lassa GP structure.

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