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Slack / Private Message Drop, p.154 [SLACK_000368] · slack_pm:msg:01581

Page text: p.154 · original PDF

Date
2020-09-07 08:49
Type
chat message · slack
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen
Topics
Vaccines

Recipients on this medium are inferred from channel membership, not per-message addressing.

Trump going to force through an EUA for _any_ vaccine by end of October is going to be the biggest - and by far most consequential - mistake America will do when it comes to COVID-19. And there's been plenty of major mistakes along the way... Not optimistic to say the least.

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StatementGradeAttributionStance
Trump going to force through an EUA for _any_ vaccine by end of October is going to be the biggest - and by far most consequential - mistake America will do when it comes to COVID-19. own voice, substantive speaker_own asserts

In context

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  1. 2020-09-07 08:46 Robert F. Garry open
    Yes - the mechanism seems to be mutation of a "premature" stop codon. However, the issue of insertions and particularly deletions (including deletions near the furin site) is a real thing - becoming a problem with the animal models according to a discussion I was having with respiratory pathogens branch at CDC on Friday - if the stocksare not properly grown [ie by passing a low MOI} the furin site gets screwed and the viruses are no longer pathogenic in animals. Related - worried about ongoing vaccine trials - rumbles are could all be major disasters inprogress under the hot spotlights [human and animal versions]. Live challenges (yes - @Kristian Andersen I agree -no placebo) may be they only way out to find vaccines that actually work.
  2. 2020-09-07 08:49 Kristian G. Andersen
    Trump going to force through an EUA for _any_ vaccine by end of October is going to be the biggest - and by far most consequential - mistake America will do when it comes to COVID-19. And there's been plenty of major mistakes along the way... Not optimistic to say the least.
  3. 2020-09-07 09:05 Robert F. Garry open
    I'm pretty sure he's going to try to do this - esp as the poll numbers either stay the same or more likely move a bit more to Biden/Harris - this is literally who he is and nothing else other than getting re-elected matters in the least -I'm also pretty sure this is going to be a line in the sand for not only the vaccine manufacturers but the FDA, NIH, even the Warp Speed commandos themselves - be ready to speak out.
  4. 2020-09-07 09:13 Andrew Rambaut open
    https://www.nytimes.com/2020/09/04/science/covid-vaccine-pharma-pledge.html
  5. 2020-09-07 09:21 Kristian G. Andersen open
    Yeah, it's crazy when "Big Pharma" should be the ones we put our trust in and not the (formerly) best protection agency in the world. It's loopy.While this announcement (if it actually comes out - but I'm sure it will) is good, it still won't prevent him from forcingthrough an EUA. I'm 99% sure it'll happen - irrespective of all the "checks and balances" in place, including statements from the main vaccine manufactures.
  6. 2020-09-07 09:28 Andrew Rambaut open
    It would still require a company to request it surely?

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