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Slack / Private Message Drop, p.138 [SLACK_000352] · slack_pm:msg:01409

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Yeah, not coming out basal for me... [shared file(s): image.png]

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-08-15 16:08 Andrew Rambaut open

Strong ascertainment bias - EVD will be noticed in that area.
2020-08-15 16:08 Kristian G. Andersen open

Ah, okay - I asked Mike if that sequence had any of the human diversity from the previous outbreak and he said no.But if it's a low coverage sample, who knows. Very very interesting (and so messed up...)
2020-08-15 16:09 Andrew Rambaut open

I will take another look before our chat.
2020-08-15 16:10 Kristian G. Andersen open

Also, interestingly - more cases of vaccinees getting primary Ebola, only to relapse later on after having receivedmAbs... This definitely needs some further looking into.
2020-08-15 16:15 Andrew Rambaut

Yeah, not coming out basal for me... [shared file(s): image.png]
2020-08-15 16:17 Andrew Rambaut open

Don't have all the 2018 genomes there for some reason.
2020-08-15 16:26 Edward C. Holmes open

Very weird indeed. Can we rule out a fuck-up?
2020-08-15 16:27 Andrew Rambaut open

The genome has a lot of low coverage bits. Are we sure they weren't doing some retrospective sequencing of 2018 samples and contaminated?
2020-08-15 16:28 Andrew Rambaut open

But then there are 11 nuc differences.