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Slack / Private Message Drop, p.17 [SLACK_000231] · slack_pm:msg:00178

Page text: p.17 · original PDF

Date
2020-05-10 05:44
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry

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The Mikovits saga is actually relevant today in another way. Here is another long-read version describing the controversy before Ian got involved: https://science.sciencemag.org/content/sci/333/6050/1694.full.pdf I remember because - This "seems very unlikely and may indicate contamination, despite the evidence presented to the contrary," the referee warned. That referee was me - based on my "PCR might get contaminated" experience with the Robt R (see Hooper above). I was the only ref of the three to vote reject. Eventually _Science_ published the paper anyway (later retracted) and one of the refs wrote a commentary that - in retrospect - was not helpful. Where the heck is he going with this rambling trip down memory lane you may ask. It's the French "NCoV-19" from December - not so much a contamination issue _per se_, but another shortcoming of PCR. Where's the cutoff?Rarely asked. What does a Ct above 30 really mean? Is there anything real there? Probably yes sometimes and probably no sometimes. Kristian said it - got to have a sequence - they have sequencers in France right?

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  1. 2020-05-10 05:44 Robert F. Garry
    The Mikovits saga is actually relevant today in another way. Here is another long-read version describing the controversy before Ian got involved: https://science.sciencemag.org/content/sci/333/6050/1694.full.pdf I remember because - This "seems very unlikely and may indicate contamination, despite the evidence presented to the contrary," the referee warned. That referee was me - based on my "PCR might get contaminated" experience with the Robt R (see Hooper above). I was the only ref of the three to vote reject. Eventually _Science_ published the paper anyway (later retracted) and one of the refs wrote a commentary that - in retrospect - was not helpful. Where the heck is he going with this rambling trip down memory lane you may ask. It's the French "NCoV-19" from December - not so much a contamination issue _per se_, but another shortcoming of PCR. Where's the cutoff?Rarely asked. What does a Ct above 30 really mean? Is there anything real there? Probably yes sometimes and probably no sometimes. Kristian said it - got to have a sequence - they have sequencers in France right?

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