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AAI18027-001-00000 Timeline/Milestones for Work: Task/Subtask Number and Name Milestones/Deliverables Due Date or Completion Date 1.0 Pre-Execution Activities Completion of internal and Completion due by six (6) external pre-execution activities I months after Task Order Award 2.1 Study Protocol (Draft) Delivery of draft Study Protocol for in vitro study Completion due by one (1) month after Task Order Award 2.2 Study Protocol (Final) Delivery of final Study Protocol Completion due by two (2) Ebola virus for in vitro study months after Task Order Award 2.3 Characterization of inhalation Completion on inhalation system I Completion due by six (6) system with Ebola virus performance with both small and I months after Task Order large particle aerosols containing I Award 2.4 Go/No-Go Meet with BTCP and NIAID sponsors review deliverables form subtask 2 and make Go/NoGo determination Completion due by six (6) months after Task Order Award 3.1 Study Protocol (Draft) Delivery of Draft Study Protocol for Small Particle Aerosol in vivo study Completion due by four (4) months after Task Order Award 3.2 Study Protocol (Final) Delivery of Final Study Protocol for Small Particle Aerosol in vivo study Completion due by four (5) months after Task Order Award 3.3 Estimation of median lethal dose of small particle aerosols Completion of the estimation of the medial lethal dose of small particle aerosols containing Ebola virus in nonhuman primates Completion due by eighteen (18) months after Task Order Award 3.4 Go/No-Go Meet with BTCP and NIAID sponsors review deliverables form subtask 3 and make Go/NoGo determination Completion due by eighteen (18) months after Task Order Award 4.1 Study Protocol (Draft) Delivery of Draft Study Protocol for Large Particle Aerosol in vivo study Completion due by eleven (11) months after Task Order Award 4.2 Study Protocol (Final) Delivery of Final Study Protocol for Large Particle Aerosol in vivo study Completion due by twelve (12) months after Task Order Award 4,3 Estimation of median lethal dose of large particle aerosols Completion of the estimation of the medial lethal dose of large particle aerosols containing Ebola virus in nonhuman primates Completion due by twentysix (26) months after Task Order Award pg. 3