COVID-19 Records

Private channel session 1379

26 messages over 1h 31m, 2021-05-15 – 2021-05-15.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2021-05-15 16:14 Edward C. Holmes open PDF p.816
    I've got to give this named lecture (relatively big locally) in a few weeks. I don't not sure whether I should: (a) ignore lab escape, (b) mention it's deficiencies politely, or (c) say fuck it and rip to shreds. I'm tempted by (c). I've been advised to keep off Twitter because of this pending FOI court case.
  2. 2021-05-15 17:06 Kristian G. Andersen open PDF p.816
    Definitely (c). Here - start with this: https://docs.google.com/document/d/17btNILyJFQccKCg7xAwETRN5LWo9g6A_haWubrywwIU/edit?usp=sharing
  3. 2021-05-15 17:07 Kristian G. Andersen open PDF p.816
    Still working on this document, but I think we have a logical structure now and most of the evidence put in. Let's turn this into a talk (you), Twitter thread (me), and then a paper.
  4. 2021-05-15 17:08 Kristian G. Andersen open PDF p.816
    I'll doodle over this this coming week, adding references, more points, etc. - but if we could all add to it, then I thinkwe have a very good start. One thing we need to see if we can more specifically address - Wuhan. People just can't get over the fact it started there and then they don't look at any of the additional evidence.
  5. 2021-05-15 17:15 Edward C. Holmes open PDF p.816
    Right. I'll go over the google doc later today. There's no epidemiological link to the WIV (and people have beensearching night and day for > a year). Simple as that. But there is a direct epidemiological link to an animal market in which CoVs have consistently emerged in the past. There is zero evidence that WIV have any virus that's the direct progenitor of SC2.
  6. 2021-05-15 17:18 Kristian G. Andersen open PDF p.816
    Yup
  7. 2021-05-15 17:25 Edward C. Holmes open PDF p.816
    I'll go for a public take down. It will probably go on Youtube so all the parasites will freak out but, frankly, fuck them.
  8. 2021-05-15 17:29 Edward C. Holmes open PDF p.817
    CoV-HKU1 was first described in Shenzhen.
  9. 2021-05-15 17:29 Kristian G. Andersen open PDF p.817
    So we really need to answer the question - how unusual is Wuhan for something like this to happen? I don't think very unusual - animal markets, top-10 largest city, largest city in central China, etc.
  10. 2021-05-15 17:29 Kristian G. Andersen open PDF p.817
    Really?
  11. 2021-05-15 17:32 Edward C. Holmes open PDF p.817
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538593/
  12. 2021-05-15 17:33 Kristian G. Andersen open PDF p.817
    ... and SARS-CoV-1 in Foshan. I mean, these are big places - like Wuhan.
  13. 2021-05-15 17:34 Edward C. Holmes open PDF p.817
    HKU-1. 1. Emerged in massive Asian city; 2. Unknown animal origin; 3. Furin cleavage site; 4. Initially associated with pneumonia. Sound familiar?
  14. 2021-05-15 17:35 Kristian G. Andersen open PDF p.817
    FUCK EDDIE - THAT CAME FROM THE LAB TOO??!!!!!!!!
  15. 2021-05-15 17:35 Kristian G. Andersen open PDF p.817
    It's the same thing all over again.
  16. 2021-05-15 17:36 Edward C. Holmes open PDF p.817
    It is! I've mentioned HKU1 in virtually every talk I've given over the last 14 months. Just look at that JVI paper. You could just transpose SARS-CoV-2 for CoV-HKU1.
  17. 2021-05-15 17:37 Kristian G. Andersen open PDF p.817
    Yeah, reading it now - it really is exactly the same story all over again. Except, more benign virus.
  18. 2021-05-15 17:38 Kristian G. Andersen open PDF p.817
    This is good - because if we can kill the "Wuhan isn't so special", it'll help turn over a lot of people. Would also help ifwe had a good sense of where major labs are.
  19. 2021-05-15 17:38 Edward C. Holmes open PDF p.817
    Initially a pneumonia patient.
  20. 2021-05-15 17:40 Edward C. Holmes open PDF p.817
    As there was no major outbreak of pneumonia people lost interest, but it's all there.
  21. 2021-05-15 17:41 Kristian G. Andersen open PDF p.818
    That's the thing - there's a huge bias towards "something odd here" when things go wrong. But HKU1 is exactly the same - minus severe disease. I can guarantee you that if H1N1 had been worse, the lab leak theory of its origin would also not have gone away.
  22. 2021-05-15 17:42 Edward C. Holmes open PDF p.818
    Totally. I think the HKU1 story is hugely instructive.
  23. 2021-05-15 17:43 Kristian G. Andersen open PDF p.818
    Eddie - would it be possible to get some data on wildlife markets in China from your contacts? Maybe that journo? I'm wondering if we could plot number or markets (or similar) across a map and show an association. Would be_hugely_ instructive, but I have no idea if Wuhan is special, or not, when it comes to these types of markets.
  24. 2021-05-15 17:43 Edward C. Holmes open PDF p.818
    I'll see what I can do.
  25. 2021-05-15 17:43 Kristian G. Andersen open PDF p.818
    I swear, if we can nail the "Wuhan" part, our job will be done.
  26. 2021-05-15 17:45 Edward C. Holmes open PDF p.818
    Yes, need to show it is not special.