COVID-19 Records

Private channel session 1086

30 messages over 4h 12m, 2021-03-10 – 2021-03-10.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2021-03-10 11:42 Edward C. Holmes open PDF p.583
    The anticipation is killing me
  2. 2021-03-10 11:56 Robert F. Garry open PDF p.583
    I just listened to the Chatham House webinar (after daisy-chaining zooms for most of the morning). The Parisitesdominated the questioning to the panel, but - good news imo the panel was ready. Judge for yourself thou. Daszak: annoying, but getting his rhetoric together. Koopmans: sharp and smooth - on point. Watson: pretty outclassed interms of communication skills, but a point or two. NO mention of Eddie's smoking raccoon dog pics, but none expected - I do think they are saving it for the release of the report.
  3. 2021-03-10 12:24 Edward C. Holmes open PDF p.583
    Did they say when the WHO report will be released? I'm sure they're saving the smoking canid and other details and which will really annoy the Parisites
  4. 2021-03-10 12:38 Robert F. Garry open PDF p.583
    They said within two weeks.
  5. 2021-03-10 13:18 Robert F. Garry open PDF p.583
    Making Parisites crazier - the gall of these ppl is amazing - clueless about viruses, but that won't stop them. [shared file(s): image.png]
  6. 2021-03-10 13:31 Edward C. Holmes open PDF p.583
    Ha, that's so stupid! :rolling_on_the_floor_laughing:
  7. 2021-03-10 13:48 Kristian G. Andersen open PDF p.583
    :rolling_on_the_floor_laughing:
  8. 2021-03-10 13:50 Kristian G. Andersen open PDF p.584
    Eddie, can you please (please!) do us a favor and reply? Maybe point her to your book on Amazon on the topic for extra snark.
  9. 2021-03-10 13:53 Edward C. Holmes open PDF p.584
    On it.
  10. 2021-03-10 14:10 Edward C. Holmes open PDF p.584
    Would this be ok? "There's a process called 'recombination' that is commonly documented in nature that explains this pattern. Coronaviruses recombine frequently. This is covered in basic virology textbooks and my own monograph: https://www.amazon.com/Evolution-Emergence-Viruses-Oxford-Ecology/dp/0199211132"
  11. 2021-03-10 14:12 Kristian G. Andersen open PDF p.584
    Sufficiently snarky - so yes.
  12. 2021-03-10 14:14 Edward C. Holmes open PDF p.584
    Done. I didn't reply because I have blocked this nutter, but I pasted that tweet in.
  13. 2021-03-10 14:15 Kristian G. Andersen open PDF p.584
    :fire:
  14. 2021-03-10 14:19 Edward C. Holmes open PDF p.584
    She is so spectacularly dumb. They just don't understand the basic biology of what they are talking about.
  15. 2021-03-10 14:21 Kristian G. Andersen open PDF p.584
    I mean - they should have come across recombination by now if they actually cared about looking at this properly... But I guess that was never the purpose.
  16. 2021-03-10 14:23 Andrew Rambaut open PDF p.584
    Found some lovely examples of recombinants between B.1.1.7 and other lineages: [shared file(s): group4_snp_plot.png]
  17. 2021-03-10 14:24 Andrew Rambaut open PDF p.584
    Perhaps that is lab made too?
  18. 2021-03-10 14:31 Edward C. Holmes open PDF p.584
    You can't argue with people so dumb.
  19. 2021-03-10 14:34 Kristian G. Andersen open PDF p.584
    Interesting recombinants - Andrew, do you have an automated way to detect these? We have seen some strange sequences lately.
  20. 2021-03-10 14:37 Andrew Rambaut open PDF p.585
    Was just looking for intermediates of B.1.1.7 - i.e., perhaps involved in the genesis events. Came across a bunch with some of the mutations but not all. The best ones were some that had multiple genomes so were clearlytransmitting - but the cool thing is they were sequenced in different labs so no lab funny business. Probably loads more but these are the low hanging fruit (about 5-6 sets)
  21. 2021-03-10 14:38 Kristian G. Andersen open PDF p.585
    Interesting - not really surprised. So Bette is right? As in, her analyses are right?
  22. 2021-03-10 14:42 Andrew Rambaut open PDF p.585
    Once again Bette got the right answer but is using flawed methods. Her 3-sequence recombination method can't distinguish recombination from convergence.
  23. 2021-03-10 14:43 Andrew Rambaut open PDF p.585
    But recombination is no surprise to any one.
  24. 2021-03-10 14:56 Kristian G. Andersen open PDF p.585
    That's what I thought - and yeah, recombination is absolutely no surprise to anybody who's been following this virus.I can assure you Bette will make full use of being wrongly right, though....
  25. 2021-03-10 15:04 Kristian G. Andersen open PDF p.585
    Eddie - you're killing me... [shared file(s): Screen Shot 2021-03-10 at 14.36.44.png]
  26. 2021-03-10 15:09 Robert F. Garry open PDF p.585
    I remember a tale of "rightfully" wrong back in the Ebola days https://science.sciencemag.org/content/353/6300/658.1.full https://pubmed.ncbi.nlm.nih.gov/27516593/ Rambaut et al show that the erratum to our report on Ebola virus Makona evolution not only corrected sample dates modified byothers in GenBank but also corrected an additional transcriptional error in our original analysis. We agree with their observation that both factors contributed to our revised evolutionary rate estimate but continue to stand by our revised estimate and conclusions.
  27. 2021-03-10 15:12 Edward C. Holmes open PDF p.585
    Oh, I remember that one well!
  28. 2021-03-10 15:48 Robert F. Garry open PDF p.585
    https://onlinelibrary.wiley.com/doi/10.1002/bies.202000325
  29. 2021-03-10 15:50 Robert F. Garry open PDF p.585
    taking Segreto and Deigin to task.
  30. 2021-03-10 15:55 Edward C. Holmes open PDF p.585
    Thank you Russia!