COVID-19 Records

Private channel session 838

30 messages over 2h 40m, 2021-01-19 – 2021-01-19.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2021-01-19 16:37 Edward C. Holmes open PDF p.425
    At the very least it's a nice counter to the 'RaTG13 ain't real' bridgade.
  2. 2021-01-19 16:46 Edward C. Holmes open PDF p.425
    Tommy is in for our post! Can someone give him access to the Google doc to edit? I doubt I have the skills to dothis. His email address is:
  3. 2021-01-19 17:05 Robert F. Garry open PDF p.425
    Great! Will modify the figure. I think not a lot of changes to text are needed - will keep those minimal...
  4. 2021-01-19 17:34 Kristian G. Andersen open PDF p.425
    Not a great day for confident immunologists. https://www.biorxiv.org/content/10.1101/2021.01.18.427166v1
  5. 2021-01-19 17:35 Kristian G. Andersen open PDF p.425
    A little better. https://www.biorxiv.org/content/10.1101/2021.01.15.426911v1
  6. 2021-01-19 17:51 Edward C. Holmes open PDF p.425
    Thanks Kristian, this is really doing wonders for my mental health.
  7. 2021-01-19 18:06 Kristian G. Andersen open PDF p.425
    You live in Australia. No sympathy.
  8. 2021-01-19 18:14 Edward C. Holmes open PDF p.426
    Fair point.
  9. 2021-01-19 18:20 Kristian G. Andersen open PDF p.426
    Looking at that bat virus I'm honestly surprised we haven't all died of coronavirus infections already. Such a wild family. Interesting to see a partial 'human' RBD
  10. 2021-01-19 18:25 Edward C. Holmes open PDF p.426
    I'm mainly looking forward to Alina and crowd trying to take it down
  11. 2021-01-19 18:32 Robert F. Garry open PDF p.426
    All the building blocks are in bats. But, I'm with Eddie in thinking that Pangos have a couple of related Pango virus lineages they are carrying - that's despite Daszak and Alina musing that the pangos get infected after they arecaptured by humans or some other captured animal. The pango that get caught are the sick ones - just like the monkeys/apes with Ebola virus are sick and get captured. The third pango cov from China pretty much seals it forme.
  12. 2021-01-19 18:35 Edward C. Holmes open PDF p.426
    Looking foward to Tommy's pango data...being sequenced now I think.
  13. 2021-01-19 18:36 Edward C. Holmes open PDF p.426
    Weifeng has written this review paper and stuck my name on it. It contains the following paragraphs: "On June 11,2020, a COVID-19 resurgence was reported in Beijing after 56 consecutive days without confirmed local cases inBeijing. By mid-June, a total of 368 cases were confirmed and epidemiological investigation linked all the confirmed cases to the Xinfadi market, suggesting a single infection source. Genomic surveillance and epidemiological investigation identified the same SARS-CoV-2 virus from the frozen salmon internationally imported in the coldstorage which sold salmon to a booth in the Xinfadi market. This outbreak highlights that cold-chain food contamination may be responsible for the resurgence in Beijing. After that China began to perform routinesurveillance of SARS-CoV-2 for cold-chain related occupational population. Similarly, the source for the COVID-19 outbreak in Qingdao Municipal Chest hospital was identified to be two stevedores responsible for internationallyimported seafood who tested positive for SARS-CoV-2 in a routine test on September 24, 2020. SARS-CoV-2nucleic was detected in cold-chain food and environmental samples and live SARS-CoV-2 was also successfully isolated from xx [Zhangyong EID], which provided direct evidence that SARS-CoV-2 contaminated seafood is ableto trigger human infections. It is worth mentioning that there were internationally and domestically imported seafoodon sale in the Huanan seafood market before it was closed on January 1, 2020. Whether contaminated cold-chain food initiated the infections at the Huanan seafood market remains elusive."
  14. 2021-01-19 18:37 Robert F. Garry open PDF p.426
    Author list? Opt 1 - switch Eddie and Kristian and make Eddie corresponding. Opt 2 leave Eddie at second and make him co-first. Not sure where to put Tommy in either case.
  15. 2021-01-19 18:37 Edward C. Holmes open PDF p.426
    "In addition, nucleic fragments of SARS-CoV-2 were also detected using PCR and sequencing approaches. For example, SARS-CoV-2 in wastewater in northern Italy using both nested RT-PCR targeting the ORF1ab region and real-rime RT-PCR targeting the RdRp region, and the earliest positive samples were dated back to December 18, 2020 in Milan and Turin [La Rosa G et al., Sci Total Environ]. Similarly, the detection of SARS-CoV-2 in wastewatersamples was also reported using real-time RT-PCR targeting the N gene, with the archived sample collected inSpain on March 12, 2019 [Randazzo et al., Water research]. The SARS-CoV-2 RNA was also detected in a patientin France in December 2019 using two different PCR-based assays and his last international travel was to Algeria inAugust 2019 [Deslandes et al., IJAA]. However, none of the three studies reported the viral sequences from the positive samples. More recently, SARS-CoV-2 RNA was identified in an oropharyngeal swab specimen collected from a child with suspected measles in Italy in early December 2019 [Amendola et al., EID]. In addition, the amplified470-bp fragment of the spike gene from the child showed 100% identical to that of SARS-CoV-2. All these studies highlight the potential cryptic spread of SARS-CoV-2 in some European countries before the first reported case inrespective country, whose implications for the origins of SARS-CoV-2 clearly require further investigation."
  16. 2021-01-19 18:37 Edward C. Holmes open PDF p.427
    You should be corresponding Bob, but I don't mind going last (or 2nd).
  17. 2021-01-19 18:38 Edward C. Holmes open PDF p.427
    Weifeng is clearly being told to tow the party line...I'm going to have to take my name off otherwise it will underminemy credibility. Thoughts?
  18. 2021-01-19 18:44 Kristian G. Andersen open PDF p.427
    Yeah, clearly a party line here - which is pretty horrible. It's the fucking blame game from the US causing this. Let's make Eddie last
  19. 2021-01-19 18:44 Kristian G. Andersen open PDF p.427
    And yeah - I'd take my name off it - language like this is going to raise eyebrows and I don't think you want to be partof that
  20. 2021-01-19 18:45 Edward C. Holmes open PDF p.427
    Agreed, thanks. I'll use all the tact I can muster to get out of this. I might offer to edit the English but not be anauthor. What a fucking mess.
  21. 2021-01-19 18:49 Kristian G. Andersen open PDF p.427
    Talking about a fucking mess - look at how Carl Z is quoting me in the NYT [shared file(s): Screen Shot 2021-01-19at 6.47.19 PM.png]
  22. 2021-01-19 18:50 Kristian G. Andersen open PDF p.427
    Now, look at my full quote [shared file(s): Screen Shot 2021-01-19 at 6.47.52 PM.png]
  23. 2021-01-19 18:50 Kristian G. Andersen open PDF p.427
    That is fucking bullshit - I trusted Carl to actual do a good job.
  24. 2021-01-19 18:50 Edward C. Holmes open PDF p.427
    Bastard! Did you correct him??
  25. 2021-01-19 18:51 Kristian G. Andersen open PDF p.427
    I didn't, but I'll push the whole quote - that's really disingenuous since it makes me sound as if I agree with these monkeys.
  26. 2021-01-19 18:57 Edward C. Holmes open PDF p.427
    Totally! Bloody out of order.
  27. 2021-01-19 19:01 Kristian G. Andersen open PDF p.428
    So unnecessary.
  28. 2021-01-19 19:06 Edward C. Holmes open PDF p.428
    Untypical of Carl as well.
  29. 2021-01-19 19:12 Kristian G. Andersen open PDF p.428
    Bad day at the office. :man-shrugging:
  30. 2021-01-19 19:17 Edward C. Holmes open PDF p.428
    Journos just can't help telling the story they want