Slack / Private Message Drop — page 348

[2020-12-29 14:26:16] [Robert Garry] https://www.statnews.com/2020/12/29/public-health-experts-grow-frustrated-with-pace-o[...]&utm_medium=em ail&utm_term=0_8cab1d7961-ed09f05acc-151385277 [2020-12-29 23:00:55] [Eddie Holmes] https://apnews.com/article/united-nations-coronavirus-pandemic-china-only-on-ap-bats-24fbadc58cee3a40bca2ddf7 a14d2955 [2020-12-30 00:48:22] [Andrew Rambaut] Best name ever for a scientist: `Dr. Supaporn Wacharapluesadee, a coronavirus expert` [2020-12-30 03:25:44] [Eddie Holmes] https://www.nytimes.com/2020/12/30/world/asia/china-coronavirus.html?action=click&module=Top%20Stories &pgtype=Homepage [2020-12-30 05:11:24] [Robert Garry] ""There's so much speculation around the origins of this virus," Mazet said. "We need to step back...and let scientists get the real answer without the finger-pointing." I guess I must be freaking biased, but this strikes me the wrong way. The release of the Cambodian CoV is important for "origins.' With long stretchs of local high similarity to RaTG13 should put the Mojiang mine story on the back burner. Still think that the WHO and Lancet "investigations" are going to do more harm than good. This AP article is not changing my mind. [2020-12-30 05:26:26] [Robert Garry] @Eddie Holmes I think the NYTimes story is good and it has one great part - talking about the release of the sequence on virological :+1::skin-tone-2: also for @Andrew Rambaut as well for heading the world's most influential virology "blog." What's "confusing" me is that Eddie is supposed to be a CCP running dog at least according to DRASTIC/Alina et al. I know that there has been other discussion about the seq release, but hope the NYT article further chips away at that notion that we're somehow under the influence of the CCP. [2020-12-30 06:00:12] [Robert Garry] [thread - ID: 2020-12-28 14:44:55] @Eddie Holmes Is the Simplot a GD pangolin? Seems like it should score higher than RaTG13 in part of the RBD. [2020-12-30 06:36:31] [Robert Garry] Important paper IMO https://www.biorxiv.org/content/10.1101/2020.12.28.424565v1 [2020-12-30 12:24:54] [Eddie Holmes] @Robert Garry Completely agree with your comments about the AP article. The focus on Yunnan could be very misguided. And I don't know what Linfa was talking about - total nonsense. [2020-12-30 14:56:56] [Robert Garry] I took the information from the channel on the SC2 spike mutations that arise on human-to-human passage and human-to-animal passage including serial passage in lab animals and put together this figure. First step was to make a Swiss model that fills in the gaps of the cryo structure. This is the complete sequence sans any disordered regions or FCS mutations. It's striking that there are so many examples of the very same mutations in the UK/South Africa variants showing up during transfers to different species. Seems to me that the mutations fall into FIVE