Slack / Private Message Drop — page 300

[Kristian Andersen] ALL the pangolins have that one - none of the bats [2020-12-06 11:12:46] [Andrew Rambaut] It is part of the pangolin which is more divergent than RmYN02 [2020-12-06 11:13:15] [Andrew Rambaut] But seems a weird coincidence given I pulled it out because of the Malaysian/Pangolin connection [2020-12-06 11:13:56] [Andrew Rambaut] Synonymous though [2020-12-06 11:13:57] [Kristian Andersen] Haha, YES - I thought you had looked at the alignment! [2020-12-06 11:14:22] [Andrew Rambaut] No - was just looking for ones related to WA1 that were from more plausible locations [2020-12-06 11:14:55] [Andrew Rambaut] Given it is synonymous and the pangolin has loads of other mutations in that area it must be coincidence. [2020-12-06 11:15:00] [Kristian Andersen] Oh, but hang on - RmYN02 has 'C' in this position too - so pangos and RmYN02 [2020-12-06 11:15:07] [Andrew Rambaut] But spooky none the less [2020-12-06 11:15:19] [Kristian Andersen] Yeah, probably - but, yes, spooky. [2020-12-06 11:15:42] [Kristian Andersen] I think it's safe to say that we're definitely missing some early emergence stuff here [2020-12-06 11:16:40] [Kristian Andersen] ... which is very interesting and worth a closer look. Would explain why we can't really root properly as well (I haven't checked recently, but back in the spring, BEAST insisted on a midpoint root when you took away the dates). [2020-12-06 11:16:47] [Andrew Rambaut] Will do some experiments on BEAST dating with enforced WA1 outgrouping [2020-12-06 11:17:29] [Kristian Andersen]