Baric Transcribed Interview (Redacted) — page 103

DC.Scheduling@LexitasLegal.com So the idea that just the virus receptor interaction and entry is the whole key to driving a virus to become a pandemic is just nonsense, and it's always been nonsense. In the case of coronaviruses, there are 49 genes in each of our bodies that regulate disease severity, and the person who gets really sick has a very common loci on chromosome three, with five genes on it, that we inherited from Neanderthals, according to the reports, based on people that do the sequence comparisons. And if you have that loci you're going to get really sick with sarbecoviruses. MS. SALAZAR: But so -- DR. BARIC: And it's nothing to do with entry. You can have scenarios where the virus grows to the exact same titer, and one person dies and the next person doesn't even know they're sick. MS. SALAZAR: But so the actual moving, the cleavage site -- DR. BARIC: Yes. MS. SALAZAR: -- into WIV1 -- DR. BARIC: Yes. MS. SALAZAR: -- is that gain-of-function? DR. BARIC: Um -- MS. SALAZAR: Because do you know what is -- DR. BARIC: It would depend on the outcomes of all the earlier experiments, right. So remember, one of those