Chat message

Slack / Private Message Drop, p.866 [SLACK_001080] · slack_pm:msg:09011

Date: 2021-05-25 03:48
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker: Andrew Rambaut

Recipients on this medium are inferred from channel membership, not per-message addressing.

@Andrew Rambaut I think the presence in human CoVs probably talks more to the bias towards spillovers from viruses that already have the FCS rather than it evolving in humans

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2021-05-25 03:46 Andrew Rambaut open

Need to nail down the bit in the letter about the FCS - having the human viruses as examples is open to a comeback. The MERS one is cool though because it is a nearby RxxR motif in the right site but it is not a human virus
2021-05-25 03:47 Andrew Rambaut open

The point is that it exists in nature in various coronaviruses in non-human animals. But seems to be important forH2H transmission.
2021-05-25 03:47 Robert F. Garry open

The Chinese absolutely positively 100% KNOW it did not come from any of their labs. But (as discussed in-channel], they are prefectly content to let Murdoch media rant and take the lead about a "lab leak." It distracts from having anyone discuss "gamey taste" and the multibillion dollar wildlife trade that they find highly embarrassing for whatever reason.
2021-05-25 03:48 Robert F. Garry open

@Andrew Rambaut Yes - spot-on!
2021-05-25 03:48 Andrew Rambaut

@Andrew Rambaut I think the presence in human CoVs probably talks more to the bias towards spillovers from viruses that already have the FCS rather than it evolving in humans
2021-05-25 03:53 Robert F. Garry open

Shi releases mine virus sequences. Hey no problem - the goalposts are highly mobile. [shared file(s): image.png]

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