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Slack / Private Message Drop, p.521 [SLACK_000735] · slack_pm:msg:05420

Page text: p.521 · original PDF

Date
2021-02-17 12:11
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Vaccines

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Yes - indeed that was my main concern - can humans recognize that epitope? Odds were good in favor, but not 100%. Good to see the data and yes - get the v.2 with Nelly, EeeK, "DorA", "DouG, Jr." and a few others into production asap. Relevant discussion after you left on the EBOV vaccine - seems that protection is rather short-livedtoo which explains the vaccinee infections, re-infections or recrudescence. Unless you stabilize those class I Viral Fusion Proteins it's hard to induce good neuts. EBOV good enough for ring vaccination, long term protection - not somuch unless you plan on vaccinating everyone against EBOV on a yearly basis.

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Relevant discussion after you left on the EBOV vaccine - seems that protection is rather short-livedtoo which explains the vaccinee infections, re-infections or recrudescence. needs context uncertain explicit hedge asserts

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  1. 2021-02-17 12:11 Robert F. Garry
    Yes - indeed that was my main concern - can humans recognize that epitope? Odds were good in favor, but not 100%. Good to see the data and yes - get the v.2 with Nelly, EeeK, "DorA", "DouG, Jr." and a few others into production asap. Relevant discussion after you left on the EBOV vaccine - seems that protection is rather short-livedtoo which explains the vaccinee infections, re-infections or recrudescence. Unless you stabilize those class I Viral Fusion Proteins it's hard to induce good neuts. EBOV good enough for ring vaccination, long term protection - not somuch unless you plan on vaccinating everyone against EBOV on a yearly basis.

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