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Slack / Private Message Drop, p.310 [SLACK_000524] · slack_pm:msg:03253

Page text: p.310 · original PDF

Date
2020-12-14 09:32
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker
Andrew Rambaut

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Oh my fuck

In context

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  1. 2020-12-14 09:03 Kristian G. Andersen open
    She _does_ talk a lot about me... :thinking_face:. I totally agree with her on this tweet though - a lot of high profile folks doing a lot of shit 'science'.
  2. 2020-12-14 09:17 Robert F. Garry open
    Don't get me started - just out of the COVID review study section - let's just say that I regret not putting in acompetitive application...
  3. 2020-12-14 09:24 Kristian G. Andersen open
    Hah. Next time
  4. 2020-12-14 09:32 Kristian G. Andersen open
    @Andrew Rambaut - what's this UK SARS2 mutation stuff everybody is talking about today?
  5. 2020-12-14 09:32 Andrew Rambaut
    Oh my fuck
  6. 2020-12-14 09:33 Kristian G. Andersen open
    Oh boy.
  7. 2020-12-14 09:33 Andrew Rambaut open
    Here is a summary I have been sending round - is that this variant has spike N501Y (similar to an outbreak in South Africa but apparently independent and unrelated) but it also has 13 other non-synonymous mutations and 3deletions. There is some evidence that it is spreading quickly in SE England but it is not clear if this just means thatR is high in this region and this is just the variant that is involved. There is no evidence that the course of infection isdifferent but data is limited. Lab work is being started urgently.There is phylogenetic evidence that 3 cases in Denmark and one in New South Wales may have been the result ofimport from the UK cluster.
  8. 2020-12-14 09:34 Andrew Rambaut open
    Some estimates that Erik Volz and I did independently suggests that this may be spreading at a higher rate than other variants but we can't rule out just the luck virus getting into high R areas.
  9. 2020-12-14 09:35 Andrew Rambaut open
    However - and this is what really interests me is the 14 mutations and 3 deletions in one short (in time) branch. Ithink this must be the result of transmission from a chronic infection.

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