Chat message

Slack / Private Message Drop, p.208 [SLACK_000422] · slack_pm:msg:02158

Date: 2020-10-02 15:05
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker: Edward C. Holmes
Topics: Furin cleavage site and molecular features

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That cleavage site paper is really interesting...a key point is that the polybasic insertion is selected against in Vero cells: that journalist from the NYT (Nicholas Wade) was trying to argue with me that passage in Vero cells was a way that the polybasic insertion could occur...clearly the conspiracy theorists have been discussing this. So, this blows itout the water.

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Statement	Grade	Attribution	Stance
That cleavage site paper is really interesting...a key point is that the polybasic insertion is selected against in Vero cells: that journalist from the NYT (Nicholas Wade) was trying to argue with me that passage in Vero cells was a way that the polybasic insertion could occur...clearly the conspiracy theorists have been discussing this.	own voice, substantive	speaker_own	asserts

Statement

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own voice, substantive

speaker_own

asserts

In context

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2020-10-02 15:02 Edward C. Holmes open

Quite a lot to catch-up on. I don't think we'll get any straight info about Trump's condition.
2020-10-02 15:05 Edward C. Holmes

That cleavage site paper is really interesting...a key point is that the polybasic insertion is selected against in Vero cells: that journalist from the NYT (Nicholas Wade) was trying to argue with me that passage in Vero cells was a way that the polybasic insertion could occur...clearly the conspiracy theorists have been discussing this. So, this blows itout the water.
2020-10-02 15:06 Kristian G. Andersen open

Not completely...
2020-10-02 15:07 Edward C. Holmes open

@Andrew Rambaut I think you could to invite Shi. Coming from you the invite might be accepted: it will deemed tobe a friendly audience.
2020-10-02 15:07 Edward C. Holmes open

Ha, I knew you'd say that!
2020-10-02 15:07 Kristian G. Andersen open

No way the virus would have gained it in Veros, but there's a non-zero chance that it could have gained it upon passage on human primary cells - e.g., human lung cells. The concern here is that we know that type of work was going on at WIV (the EgoHealth stuff), so we certainly can't dismiss it based on this. Hence Bob needs to do the experiment :wink:

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