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Slack / Private Message Drop, p.178 [SLACK_000392] · slack_pm:msg:01831

Date: 2020-09-17 08:13
Type: chat message · slack
recipient: Kristian G. Andersen, Robert F. Garry, Edward C. Holmes
speaker: Andrew Rambaut

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> Update from Vegard: ```Quick update: We were in the end able to obtain a decent assembly of RaTG13. The description of their approachis lacking to say the least, but the genome seems legit enough, and seems extremely unlikely to involve any sort offraud.We'll post a little commenn on virological, as there might be others looking into the same question.```

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2020-09-17 07:01 Andrew Rambaut open

I guess the question is has there been any 'imputation'? From the above it would seem they can't even get the consensus when they map to the actual consensus?
2020-09-17 07:03 Andrew Rambaut open

It would also matter which bits are low coverage. I would prefer to move on but it would be good to be armed with the knowledge - who knows where this will go next.
2020-09-17 07:10 Kristian G. Andersen open

I suspect the data is scattered across repos
2020-09-17 08:07 Robert F. Garry open

I agree with Andrew that the main point is that our analysis would not have changed much at all without RaTG13. The pangolin CoVs (that Alina seems focused on) and other BtCoVs were sufficient for the Proximal Origins analysis. I do recall a PR that talked of a 99% CoV that unfortunately never came.
2020-09-17 08:13 Andrew Rambaut

> Update from Vegard: ```Quick update: We were in the end able to obtain a decent assembly of RaTG13. The description of their approachis lacking to say the least, but the genome seems legit enough, and seems extremely unlikely to involve any sort offraud.We'll post a little commenn on virological, as there might be others looking into the same question.```
2020-09-17 08:14 Kristian G. Andersen open

Hah - I'm glad they're so thorough before bugging other scientists... I'm downloading the raw data now - lemme have a quick look
2020-09-17 09:05 Kristian G. Andersen open

Yeah, no concerns really @Andrew Rambaut [shared file(s): RaTG13.jpg]
2020-09-17 09:06 Kristian G. Andersen open

Very few unresolved bases (a handful)
2020-09-17 09:09 Robert F. Garry open

Good to see - Is there an analysis of the pango data? That seems to be a sticking point as well.

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