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Slack / Private Message Drop, p.162 [SLACK_000376] · slack_pm:msg:01659

Page text: p.162 · original PDF

Date
2020-09-14 05:44
Type
chat message · slack
recipient
Kristian G. Andersen, Edward C. Holmes, Andrew Rambaut
speaker
Robert F. Garry
Topics
Furin cleavage site and molecular features

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"tiny sample of these viruses from nature" Yes - limiting. But, I'm really curious how your snake toroviruses andserpentoviruses (that are pretty potent pathogens) fit into your tree above . Also that cluster with the pacific salmonnidovirus is really interesting. The salmon virus is the only one I found and it's spike is very interesting to say the least. Here's what i think is the pacific salmon nidovirus s1/s2 junction:ISEAINKVVEAFSHYS*RVTR*TV*RR*VITNTISA*RRRR*STDYGGGVHSN. Three-ish furin sites surrounded bypredicted O-linked glycans.

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  1. 2020-09-14 05:44 Robert F. Garry
    "tiny sample of these viruses from nature" Yes - limiting. But, I'm really curious how your snake toroviruses andserpentoviruses (that are pretty potent pathogens) fit into your tree above . Also that cluster with the pacific salmonnidovirus is really interesting. The salmon virus is the only one I found and it's spike is very interesting to say the least. Here's what i think is the pacific salmon nidovirus s1/s2 junction:ISEAINKVVEAFSHYS*RVTR*TV*RR*VITNTISA*RRRR*STDYGGGVHSN. Three-ish furin sites surrounded bypredicted O-linked glycans.

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