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Slack / Private Message Drop, p.91 [SLACK_000305] · slack_pm:msg:00926

Page text: p.91 · original PDF

Date
2020-07-01 13:57
Type
chat message · slack
mentioned
Edward C. Holmes
recipient
Robert F. Garry, Edward C. Holmes, Andrew Rambaut
speaker
Kristian G. Andersen

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From Bette's paper "A two-sided Fisher's exact test compares the counts in the pre-onset period to the counts after the two-week delay period and provides a p- value against the null hypothesis that the fraction of D614 vs G614sequences did not change". Really? This got through peer review? @Eddie Holmes, I'm pretty darn sure you must have flagged this - that's not how that test works. Or is she just using this as an inclusion criteria?

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  1. 2020-07-01 13:57 Kristian G. Andersen
    From Bette's paper "A two-sided Fisher's exact test compares the counts in the pre-onset period to the counts after the two-week delay period and provides a p- value against the null hypothesis that the fraction of D614 vs G614sequences did not change". Really? This got through peer review? @Eddie Holmes, I'm pretty darn sure you must have flagged this - that's not how that test works. Or is she just using this as an inclusion criteria?
  2. 2020-07-01 14:01 Andrew Rambaut open
    And counts are just numbers of sequences in gisaid?
  3. 2020-07-01 14:01 Kristian G. Andersen open
    Yes. Solid stuff.
  4. 2020-07-01 14:12 Edward C. Holmes open
    I said the whole analysis was crap and needed to be redone. I never saw any response to this.
  5. 2020-07-01 14:17 Edward C. Holmes open
    I submitted my review on June 12th (I only reviewed the revision). Given the speed of all this - and they wanted totake a look in 48 hours - it was clear that Cell were going to take it whatever I said. I've not looked at the paper - Ican't stand to - but I assume they've not made any of the revisions I suggested.

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