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Slack / Private Message Drop, pp.76-77 [SLACK_000290] · slack_pm:msg:00774

Page text: p.76, p.77 · original PDF

Date
2020-06-13 03:26
Type
chat message · slack
recipient
Kristian G. Andersen, Robert F. Garry, Andrew Rambaut
speaker
Edward C. Holmes
Topics
Natural origin / zoonotic spilloverWuhan Institute of Virology collaboration

Recipients on this medium are inferred from channel membership, not per-message addressing.

We have two choices: just ignore it or make a group response. I vote for the former, because I am so tired of all this, although it is deeply irritating that we raised all these concerns ourselves months ago and the tone of the email isthat we are guilty of something, or trying to cover up. Also, many of the points are stupid/wrong: (i) why anyone would have a pangolin virus in the lab is beyond me and obviously idiotic. That Viruses paper on the pangolin virus, which does not even describe the sequence, was published online in Oct. 24th 2019. It's obviously not credible tohave read this, got the pangolins and the viruses and done the leaky experiments in this timeline; (ii) the WIV is not the only lab with closely related bat viruses - obviously RmYN02 comes from a different lab; (iii) I don't see that 4amino acid insertion and no flanking changes is at all problematic, particularly as these insertions are so commone.g. in H7N7 AIV the sequence went from PEIPKGR (low path) to PEIP*KRRR*R (high path). And Bill Gallaher'stheory explains it. But most of all I am completely tired all this. Nor do I want to die on the hill - it's up to the WIV todeal with this, not us.

Extracted statements

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StatementGradeAttributionStance
Also, many of the points are stupid/wrong: (i) why anyone would have a pangolin virus in the lab is beyond me and obviously idiotic. quoted / not their view hypothetical conditional framing asserts
That Viruses paper on the pangolin virus, which does not even describe the sequence, was published online in Oct. 24th 2019. own voice, substantive speaker_own asserts
It's obviously not credible tohave read this, got the pangolins and the viruses and done the leaky experiments in this timeline; (ii) the WIV is not the only lab with closely related bat viruses - obviously RmYN02 comes from a different lab; (iii) I don't see that 4amino acid insertion and no flanking changes is at all problematic, particularly as these insertions are so commone.g. in H7N7 AIV the sequence went from PEIPKGR (low path) to PEIP*KRRR*R (high path). own voice, substantive speaker_own asserts

In context

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  1. 2020-06-13 02:43 Edward C. Holmes open
    I honestly can't take much more of this. It will be the death of me. A pangolin is the obvious animal you'd have in the lab.
  2. 2020-06-13 02:47 Edward C. Holmes open
    By the way, I think it might be Pain-Hobson, although it sounds like it he has other people as well.
  3. 2020-06-13 03:26 Edward C. Holmes
    We have two choices: just ignore it or make a group response. I vote for the former, because I am so tired of all this, although it is deeply irritating that we raised all these concerns ourselves months ago and the tone of the email isthat we are guilty of something, or trying to cover up. Also, many of the points are stupid/wrong: (i) why anyone would have a pangolin virus in the lab is beyond me and obviously idiotic. That Viruses paper on the pangolin virus, which does not even describe the sequence, was published online in Oct. 24th 2019. It's obviously not credible tohave read this, got the pangolins and the viruses and done the leaky experiments in this timeline; (ii) the WIV is not the only lab with closely related bat viruses - obviously RmYN02 comes from a different lab; (iii) I don't see that 4amino acid insertion and no flanking changes is at all problematic, particularly as these insertions are so commone.g. in H7N7 AIV the sequence went from PEIPKGR (low path) to PEIP*KRRR*R (high path). And Bill Gallaher'stheory explains it. But most of all I am completely tired all this. Nor do I want to die on the hill - it's up to the WIV todeal with this, not us.
  4. 2020-06-13 04:05 Edward C. Holmes open
    Just sent an email as well (which I now think is probably unnecessary).
  5. 2020-06-13 04:05 Andrew Rambaut open
    Totally agreed. I have talked to a few journalists about the origins recently but only if they seem genuinely interestedin the natural origins. My approach has been to keep pushing how plausible it is and ignore anything that is trying toset up lab origins without actual evidence.

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