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Slack / Private Message Drop, p.73 [SLACK_000287] · slack_pm:msg:00735

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Just making some dinner - let's Zoom in ~30mins?

In context

A single line often inverts meaning once you see what it answers, so neighbouring messages are always shown.

2020-06-11 17:21 Kristian G. Andersen open

Unclear to me if they published sequences of all these viruses - it's a lot and names are changing over time (e.g.,RaTG13 had a different name previously).
2020-06-11 17:23 Kristian G. Andersen open

And yes - of the six key mutations in the RBD, one of them occur in tissue culture for SARS (*but* it's also present inthe pangolin RBD).
2020-06-11 17:27 Edward C. Holmes open

Are you saying they deliberately inserted the furin cleavage site? I see no evidence of them ever doing that before. (Idon't think RaTG13 had a different name...I think there a partial sequence from another virus that is identical. Canwe do a quick zoom?
2020-06-11 17:38 Edward C. Holmes open

To me, "Loss of furin site in tissue culture meaning it's active" strongly argues AGAINST culturing as being the cause of the cleavage site insertion.
2020-06-11 17:44 Kristian G. Andersen

Just making some dinner - let's Zoom in ~30mins?
2020-06-11 17:47 Edward C. Holmes open

Let's say 6:30 pm time. OK?
2020-06-11 18:29 Edward C. Holmes open

https://uni-sydney.zoom.us/j/98148315438
2020-06-11 18:30 Kristian G. Andersen open

I'm on!