Transcript segment
Baric Transcribed Interview (Redacted), p.16 · baric_ti:utt:00071
Page text: p.16 · original PDF
- Date
- 2026-04-10 09:00 (day precision)
- Type
- transcript segment · interview
- recipient
- Christina Salazar, Harry Kazenoff, David T. Lambeth III, William Henderson, Clark Ervin, Jake Greenberg
- speaker
- Ralph S. Baric
- Topics
- Vaccines
Oh, we compared it to a killed vaccine.
We'd also tested alpha virus-based vaccines, Venezuelan
equine encephalitis replicon particles. It was basically
an RNA virus where the structural genes have been removed,
so it's single hit. It can only infect one set of cells.
It delivers the payload gene, in this case the coronavirus
antigen. That induces an immune response that is either
protective or not, depending on the model system.
The other was killed vaccines. In 2003, the NIH had
purchased two, or the Federal Government had purchased two
$20 million killed vaccines to test against SARS
coronavirus.