COVID-19 Records

Private channel session 990

29 messages over 1h 14m, 2021-02-17 – 2021-02-17.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2021-02-17 13:45 Andrew Rambaut open PDF p.521
    Ah Laura.. [shared file(s): image.png]
  2. 2021-02-17 13:45 Andrew Rambaut open PDF p.521
    Your silly mutation nicknames are too white and you didn't consult the ICTV!
  3. 2021-02-17 13:45 Kristian G. Andersen open PDF p.521
    Lol
  4. 2021-02-17 13:55 Kristian G. Andersen open PDF p.521
    https://www.theguardian.com/world/2021/feb/17/uk-to-begin-worlds-first-covid-human-challenge-study-within-weeks ?CMP=share_btn_tw
  5. 2021-02-17 13:56 Kristian G. Andersen open PDF p.521
    "They will be exposed to the coronavirus in a safe, controlled environment". Define "safe". :wink:
  6. 2021-02-17 14:06 Robert F. Garry open PDF p.521
    NellY - (black rapper), Pooh (a talking Bear), EeeK (what you would do if a bear talked to you) , LeiF (dead Norseman). KaitlyN, DorA, But OK maybe go with DenG instead of Doug.
  7. 2021-02-17 14:08 Robert F. Garry open PDF p.521
    :face_with_rolling_eyes:
  8. 2021-02-17 14:09 Andrew Rambaut open PDF p.521
    This is getting mental: [shared file(s): image.png]
  9. 2021-02-17 14:13 Kristian G. Andersen open PDF p.521
    She's a plant biologist and TED fellow Andrew - you're never gonna win.
  10. 2021-02-17 14:14 Andrew Rambaut open PDF p.521
    I know her twitter rants well.
  11. 2021-02-17 14:15 Kristian G. Andersen open PDF p.522
    I don't know her - but I was just on a three hour meeting with Bette Korber so I can't take any more ranting today.:firecracker:
  12. 2021-02-17 14:17 Kristian G. Andersen open PDF p.522
    I get the sense Aine's got this one down though.:clap: [shared file(s): Screen Shot 2021-02-17 at 2.17.23 PM.png]
  13. 2021-02-17 14:18 Andrew Rambaut open PDF p.522
    Ooh yours must have been the call she had to leave mine to go to.
  14. 2021-02-17 14:19 Andrew Rambaut open PDF p.522
    (Korber, I mean)
  15. 2021-02-17 14:19 Robert F. Garry open PDF p.522
    Laura seems nice. Good sense of humor. Grounded. Knows what's important. Doesn't sweat the small stuff. Focused.
  16. 2021-02-17 14:19 Andrew Rambaut open PDF p.522
    That totally sums her up.
  17. 2021-02-17 14:19 Andrew Rambaut open PDF p.522
    Oli, Nick and I were talking to Korber about your recombination problem in California
  18. 2021-02-17 14:20 Kristian G. Andersen open PDF p.522
    She would give zero information - what does she have?
  19. 2021-02-17 14:28 Andrew Rambaut open PDF p.522
    Yup.
  20. 2021-02-17 14:29 Andrew Rambaut open PDF p.522
    She told us how you find recombination
  21. 2021-02-17 14:31 Andrew Rambaut open PDF p.522
    Basically they have lots of recurrent mutations (I say, they have - I mean they have found in other people's data). Most are clearly just homoplasies being brought up by epistatic effects. Their only argument is that they are rare globally.
  22. 2021-02-17 14:33 Andrew Rambaut open PDF p.522
    She showed one picture that looked like a convincing case because it had 2 parents and good tracts of recombination (i.e., the entire spike) but was either a lab artifact, or a coinfected individual with a messed upconsensus or an actual unusual recombination. None of it matters though - clearly recombination is massively important to within host evolution and vanishingly unimportant to population evolution except in so far as the first leads to the second
  23. 2021-02-17 14:34 Edward C. Holmes open PDF p.523
    As for Laura Boykin - idiotic nonsense. I'm not sure how B.1.1.7 counts as white.
  24. 2021-02-17 14:35 Andrew Rambaut open PDF p.523
    I think she is confused.
  25. 2021-02-17 14:35 Edward C. Holmes open PDF p.523
    @Robert Garry I've gone through the text again Bob - looks good. I'm happy with the cuts.
  26. 2021-02-17 14:37 Robert F. Garry open PDF p.523
    THANKS Eddie _ I'll clean it up a bit more for Andrew and Kristian...
  27. 2021-02-17 14:44 Kristian G. Andersen open PDF p.523
    @Andrew Rambaut Very clear... Glad she had a chance to teach you how to do it properly.
  28. 2021-02-17 14:58 Robert F. Garry open PDF p.523
    https://www.biorxiv.org/content/10.1101/2021.02.05.429982v1
  29. 2021-02-17 14:59 Kristian G. Andersen open PDF p.523
    Ohhhhhh, we rock SO much! :boom: