Private channel session 905

14 messages over 57m, 2021-02-01 – 2021-02-01.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

1. 2021-02-01 14:21 Edward C. Holmes open PDF p.472
   Thanks for doing that Bob. We did notice the similarity between HA379 and GD pango in parts of the sequence. Good point about HA321, HA363 and HA442. I'll check that with Weifeng. Attached is a tree with the species marked. [shared file(s): Fig_BetaV3.2_RdRp_tidy_AIv1.pdf]
2. 2021-02-01 14:28 Andrew Rambaut open PDF p.472
   @Kristian Andersen Seem to have 52 in a simple search.
3. 2021-02-01 14:30 Kristian G. Andersen open PDF p.472
   @Kristian Andersen OK - might just be founder on our end. I just don't understand why additional mutations that get added to B.1.1.7 continue to primarily be non-synonymous....
4. 2021-02-01 14:34 Andrew Rambaut open PDF p.472
   @Kristian Andersen Actually 25 in England
5. 2021-02-01 14:48 Andrew Rambaut open PDF p.472
   @Kristian Andersen There may be a couple of independent origins of K1191N here (because this is only B.1.1.7 with K1191N) but looks like a founder to the US from UK. [shared file(s): K1191N.tree.png]
6. 2021-02-01 14:49 Andrew Rambaut open PDF p.472
   No you can't have your own variant. Their ours.
7. 2021-02-01 14:50 Kristian G. Andersen open PDF p.472
   @Kristian Andersen OK, thanks - makes sense since we see them in almost all (all?) Florida genomes, so I think itjust hitched a ride across the ocean. At least you didn't give us Eeek - yet... I suspect we'll see that fucker pop up byhimself here too.
8. 2021-02-01 15:03 Andrew Rambaut open PDF p.472
   @Kristian Andersen 175 USA genomes with Eek.
9. 2021-02-01 15:04 Andrew Rambaut open PDF p.473
   @Kristian Andersen Picking one at random... [shared file(s): image.png]
10. 2021-02-01 15:05 Andrew Rambaut open PDF p.473
    @Kristian Andersen That one has 69/70 deletion too.
11. 2021-02-01 15:05 Andrew Rambaut open PDF p.473
    @Kristian Andersen 25 of them are P.2 from Brazil
12. 2021-02-01 15:17 Kristian G. Andersen open PDF p.473
    @Kristian Andersen Yeah, but none of them are B.1.1.7, right?
13. 2021-02-01 15:17 Andrew Rambaut open PDF p.473
    @Kristian Andersen No.
14. 2021-02-01 15:18 Kristian G. Andersen open PDF p.473
    @Kristian Andersen I'm sure that'll change... It'll be interesting to see how those will compete with good old B.1.1.7