Private channel session 879

22 messages over 1h 17m, 2021-01-27 – 2021-01-27.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

2021-01-27 01:03 Edward C. Holmes open PDF p.457

Apparently Linfa only has positive serology for the pangos. No sequences.
2021-01-27 01:11 Robert F. Garry open PDF p.457

Good to know! Impressive nonetheless - can you ask him what secondary reagent he used for the pango elisa? We've been considering doing it too in Africa but you cant buy anti- pango IgG. Maybe cat, dog or ferret???
2021-01-27 01:13 Robert F. Garry open PDF p.457

THe other option is a blockade of binding assay (BOB!) but not as satisfying.
2021-01-27 01:29 Edward C. Holmes open PDF p.457

I'll see what I can find out. My mate at CNN just told that some people - I wonder who - are suggesting that cambobat spike is the result of GoF experiment. FFS. I despise these people more each day.
2021-01-27 01:38 Robert F. Garry open PDF p.457

Thanks Mazet on the cambobat paper - guilt by association.
2021-01-27 01:41 Robert F. Garry open PDF p.457

Yes Billy, Yuri and the DRASTIC crowd going nuts...as @Kristian Andersen said data/smata they'll just move the goalposts.
2021-01-27 01:42 Edward C. Holmes open PDF p.457

Apparently, the PREDICT crowd got added after they claimed it was their sample.
2021-01-27 01:48 Robert F. Garry open PDF p.457

They said same about GD pango of course which is why pango serology is important. Pango actually carry the virus.
2021-01-27 01:50 Edward C. Holmes open PDF p.457

Which is what I always thought!! I never really believed the single outbreak stuff because there are 2 pango lineages.
2021-01-27 01:55 Andrew Rambaut open PDF p.457

The question is whether the progenitor of SC2 is endemic in Chinese pangos or Malaysian ones and is being imported. I think Chinese pangos are pretty thin on the ground these days for obvious reasons.
2021-01-27 01:55 Robert F. Garry open PDF p.458

@Eddie Holmes Typical - surprised she's not first author. First/last authors on all papers was the "deal" Metabiota[Wolfe/@longcovidfaker] made with all their predict sites.
2021-01-27 01:56 Andrew Rambaut open PDF p.458

Or the pangos are just susceptible to most of the viruses in this branch of serbecoviruses
2021-01-27 01:56 Edward C. Holmes open PDF p.458

@Eddie Holmes Indeed. But the Cambodians insisted it wasn't their sample.
2021-01-27 01:57 Andrew Rambaut open PDF p.458

Clearly the branch is widely distributed in bats
2021-01-27 02:00 Robert F. Garry open PDF p.458

Good points Andrew - China imports a LOT of pangos from Africa too, so we're on a full court press to see if we can find any pango covs there...
2021-01-27 02:00 Edward C. Holmes open PDF p.458

The Yunnan pango sequence is close to those from Guangxi. Serology suggests positive animals in Thailand and Malaysia (i.e. Tommy).
2021-01-27 02:01 Edward C. Holmes open PDF p.458

Really hope Tommy's viruses get sequenced soon.
2021-01-27 02:02 Edward C. Holmes open PDF p.458

Not intermediate hosts but the ecology is really interesting.
2021-01-27 02:02 Robert F. Garry open PDF p.458

Good to know too - any insights into what secondaries [cat, dog, ferret] work would be helpful.
2021-01-27 02:11 Edward C. Holmes open PDF p.458

I thought of the DRASTIC crew getting so upset over this does warm the heart. Bless.
2021-01-27 02:18 Andrew Rambaut open PDF p.458

Has it got to the point where they say it is a fake?
2021-01-27 02:20 Edward C. Holmes open PDF p.458

I can't look at them: I get told 2nd hand. I bet Alina will be questioning research integrity.