Private channel session 876
36 messages over 4h 6m, 2021-01-26 – 2021-01-26.
A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.
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Yeah, saw parts of it - so dumb.
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Separately - I think they might want to look up GOF in a dictionary...
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At least the gorilla is doing OK even thou infected with ~LucifeR~ "LesteR." Or pick your own name LenoiR, LuthoRalso possibilities.
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Yeah, we might need to find a name for that one - last sequencing run, ~50% LesteR....
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I suspect Lester and Nelly will have to battle it out - should be interesting.
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@Andrew Rambaut is the go to for names...
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Google Scholar is now indexing Virological... :wink: [shared file(s): Screen Shot 2021-01-26 at 7.44.40 AM.png]
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Enjoy - all 191 pages of it... [shared file(s): 2021-01-26_SQuay_Bayesian Analysis of SARS-CoV-2.pdf]
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How do these people have so much time on their hands?
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Just saw it... I have no idea - I guess it's all they do?
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I like the pacman logo though
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I should point out that Trevor was / is working on a Bayesian framework for this as well. Picking priors is a littlesketchy...
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We should reply to tell him that. Perhaps they could collaborate
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That'd be fun! I do have _some_ respect for Quay though - he noticed the early ENA samples - still not explained.
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Cambodian bat genomes - just the variable loop: [shared file(s): image.png]
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Rooted by other pangolins
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Just a matter of time before we see a near-perfect match to the RBD in bats,
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Here's that nucleotide alignment of spike at 30,000 feet - from the ATG to the FCS- not the mess I thought it wouldbe - you can clearly see the indels. To Kristian's point - the RBD actually aligns pretty well. [shared file(s): image.png]
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And a bit of S2 - highly conserved at the amino acid level - but you can clearly see many instances of the ** ** **pattern, with the mismatches being the "wobble" base in the triplet. Designed by nature not a supervillain. [shared file(s): image.png]
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Cara is trying again to get me to come to China: [shared file(s): image.png]
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This time she has a name for the organisation.
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If you look up "North American Foundation for Science and Technology" you get this very convincing website: https://www.northamericanfoundationforscienceandtechnology.com
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https://www.northamericanfoundationforscienceandtechnology.com/our-team
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shared file(s): image.png
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Weed and stem cells - seems like a natural to me. Cara seems nice too, but might just be a bit of a trap...
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A trap? Surely not: `
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Love the URL - a little hard to memorize, but still. Stellar.
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Address linked to Exosomecure Research Foundation too - I suspect Johnny's home address. Nice area.
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So, the real question arises. In one case - Andrew's email - Cara is Cara Li. But on the website the Cara is CaraDong. More than one Cara? Cara got married and changed her name?
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I think this may be a job for Alina or DRASTIC...
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OMG the inconsistencies! Clearly came from the lab.
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MW251308 to MW251312
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Yuri has moved up to clustal W - however the Thai bat viruses are interesting [shared file(s): image.png]
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Their obsession with the FCS will backfire - we'll get viruses with more similar insertions and then their main argument becomes completely mute. Of course, they'll just move the goal post.
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RmYN02 like cleavage site [shared file(s): image.png]
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MW251308 this is Linfa and apparently he has some Thai pangos as well..... [shared file(s): image.png]