COVID-19 Records

Private channel session 534

4 messages over 34m, 2020-11-04 – 2020-11-04.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

  1. 2020-11-04 14:29 Andrew Rambaut open PDF p.249
    Actually, I have some inside information from WHO (please keep confidential): > We have tested a variant with four simultaneous changes in the spike protein (Amino acid changes: 69del, Y453F, I692V, M1229I). This variant has been found in five minkfarms and also in humans in the surrounding community. A complete GISAID upload of all Danish Sars-CoV-2 sequences of human origin is planned for the end of week 45. We have cultured this virus from a human patient and evaluated whether it was sensitive to neutralizing antibodies (antisera) from a collection of sera from convalescent COVID-19 patients. We found that this virus showed less sensitivity (resistance) for neutralizing antibodies from persons with previous COVID-19 infection.
  2. 2020-11-04 14:29 Andrew Rambaut open PDF p.249
    Why they are not releasing this information and the data I don't know.
  3. 2020-11-04 14:53 Edward C. Holmes open PDF p.249
    Interesting. Looking forward to the press on this one.
  4. 2020-11-04 15:03 Robert F. Garry open PDF p.250
    Opinion: To stop the next pandemic, we need to unravel the origins of COVID-19 View ORCID Profile David A. Relman PNAS first published November 3, 2020; https://doi.org/10.1073/pnas.2021133117