Slack / Private Message Drop — page 457

[2021-01-26 18:14:07] [Kristian Andersen] No, it really isn't - more of a genome announcement (although, quite a genome!) [2021-01-26 18:16:25] [Eddie Holmes] Yes, it's a beaut. [2021-01-26 18:19:49] [Robert Garry] They had lots of opportunities to really get into sarbecovirus evolution -they didn't. [2021-01-27 01:03:02] [Eddie Holmes] Apparently Linfa only has positive serology for the pangos. No sequences. [2021-01-27 01:11:12] [Robert Garry] Good to know! Impressive nonetheless - can you ask him what secondary reagent he used for the pango elisa? We've been considering doing it too in Africa but you cant buy anti- pango IgG. Maybe cat, dog or ferret??? [2021-01-27 01:13:00] [Robert Garry] THe other option is a blockade of binding assay (BOB!) but not as satisfying. [2021-01-27 01:29:48] [Eddie Holmes] I'll see what I can find out. My mate at CNN just told that some people - I wonder who - are suggesting that cambobat spike is the result of GoF experiment. FFS. I despise these people more each day. [2021-01-27 01:38:04] [Robert Garry] Thanks Mazet on the cambobat paper - guilt by association. [2021-01-27 01:41:38] [Robert Garry] Yes Billy, Yuri and the DRASTIC crowd going nuts...as @Kristian Andersen said data/smata they'll just move the goalposts. [2021-01-27 01:42:35] [Eddie Holmes] [thread - ID: 2021-01-27 01:42:35] Apparently, the PREDICT crowd got added after they claimed it was their sample. [2021-01-27 01:48:56] [Robert Garry] They said same about GD pango of course which is why pango serology is important. Pango actually carry the virus. [2021-01-27 01:50:04] [Eddie Holmes] Which is what I always thought!! I never really believed the single outbreak stuff because there are 2 pango lineages. [2021-01-27 01:55:36] [Andrew Rambaut]