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Gates Package — page 844

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A HDAd-EF 1a.ABE8e t &P_, Be im, ce week 16-P sy cs7BV6 B-YAC/ -- BMlin-cells C5TBV6 week 16-S CO46IG) lin-cells. >> --_ i peecalaer analysis B (ey D ° * ASG } g # ABC (A1AG) s pee ° J < 2 60 : 60; A 40: Ps 2 40 x A 20: a : ; as e fread i eae a eee s E transplant 16w , 100 m= Ac s Ss mm A>G ge ge mmr ADT z é a5 ge gs 8B o4 2B oo, FZ oo = 2001 F £ 0.001 0.001 A5 AB AQ Alt A5 AB AQ AI1 F Mutation position distribution G #4207 82.2% (144964) ae = nonedited oa = [== monoallelic == biallelic S050, (18971) £ = Pare g 3 493% (00078 = % BR g © * S 32.9% (7985). Ss ie ne = 00 16.4% (28992). LEIS S eS ia ee Se Reference amplicon position (bp) "se iS Fig.5

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gates:exh:00284 attachment 844