Gates Package — page 1358

@ DEVELOP ORAL BIOLOGICS Solving immune deficiencies How do we produce and deliver biologics into the gut such that they are stable, active, and durable? What will this contain? Potential platforms Deficient colostrum/ milk Scalable platforms that allow for production of low-cost, gut-directed interventions @ Adaptive immunity @ Innate immunity @ Human milk oligosaccharides Synthetic colostrum/ milk as a supplement to improve gut health of humans and animals @ Microbiome, cytokines, etc. PARTNERS: INCENTIVES: Regulatory measures/endpoints for approval of oral val af . *'MassBio' WENTALA BACTOLIFE -- antibody cocktails, price/ volume guarantees (to be developed) BIOSCIENCE LUMEN BIOSCIENGE G if Not for distribution