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From: "Handley, Gray (NIH/NIAID) [E]" <{BB@niaid nih. gov> To: "Varmus, Harold (NIH/NCI) [E]" <EOnih.gov> Ce: "Fauci, Anthony (NIH/NIAID) [E]" <{if@niaid.nih.gov>, "Pineda, Mark (NIH/NIAID) (E]" EEO niaid.nih.gov>, "Hedje, Judith (NIH/NIAID) [E]" <{{§f@niaid.nih.gov> Subject: RE: MRTC in Bamako Date: Wed, 17 Apr 2013 15:13:57 -0400 Importance: Normal Dr. Varmus: Since 1990, NIAID has spent about $2.1 M in partnership with the University in Mali to upgrade the infrastructure that is on the FMPOS campus and five field sites -- which constitutes the Mali ICER/MRTC. These funds have come from NIAID, the Rockefeller Foundation and the US Embassy. USAID also provided a small amount of support for this program in its early years. In all cases, resources helped support both infrastructure and program costs. Considerable investment has been made by the FMPOS itself, but we have no way to document that. In addition, we have invested in essential IT infrastructure to support multiple projects and ICER operations. Since 2000, this investment has been about $1.7 M. This includes maintenance, services, hardware, software, local human capital investment, and travel. This figure does not capture elements of the Mali ICER IT system that were part of services and systems provided to the entire ICER network. Obviously, in all these expenditure estimates, there is no capture of NIH staff costs. In addition, utilizing and sustaining this infrastructure, NIAID has expended about $141 M over the last 21 years to support research projects and programs at the Mali ICER - $57 K in extramural grants and contracts and $84 K in intramural research project support. In addition, NIMH, FIC and the OD also have funded ICER-associated research projects. This has been only a few million dollars, but still has been significant. Please let me know if this data does not meet your need or if you have other questions. Gray From: Varmus, Harold (NIH/NCI) [E] Sent: Thursday, April 11, 2013 4:07 PM To: Handley, Gray (NIH/NIAID) [E] Subject: Re: MRTC in Bamako Gray, many thanks. I'Il be reviewing these items over the weekend and will look forward to the numbers next week. On 4/11/13 2:11 PM, "Handley, Gray (NIH/NIAID) [E]" <O niaid.nih.gov> wrote: Dr. Varmus: Attached is background information on the ICER in Mali. I am sending what I have gathered so far -- two documents prepared for different purposes, which describe this long-term engagement. So far, I am still pulling together information about overall funding, although the "History" piece includes some recent information. Gathering this data is challenging because much of the early support was from a variety of sources including Foundations and USAID. I will send at least a ball-park figure next week. Yesterday, the ICER programs all presented on their current studies so I will also try to share the slides related to the Mali program. These well illustrated some aspects of the history and the current breadth of our scientific engagement there.

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gates:exh:00056 attachment 133
Re: MRTC in Bamako 2013-04-11 email 133–134