Attachment
Gates Package, p.30 · gates:exh:00018
Page text: p.30 · original PDF
- Date
- — (unknown precision)
- Type
- attachment · document
First NHP Study Results - Preliminary
Two arm, vehicle controlled study administering
favipiravir once a day by oral gavage
Favipiravir 400 mg/kg/d once followed by 200mg/kg/d for
13 days
Animals sedated once a day to protect technician
EBOV challenge four days after beginning favipiravir
Control monkeys died within the expected timeframe
One test animal survived to Day 28, the others lived
longer
than controls
Viral titers suggested antiviral effect
Suggestion of GI abnormalities
Histology, PK pending
Audit of study pending
Confidential