A single line often inverts meaning once you see what it
answers, so neighbouring messages are always shown.
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Nov. 4, 2022 I received the call today from David Ho who had recently published a preprint article showing that the neutralizing antibody response against the BA4/5 variant induced by the bivalent BA 4/5 boost versus the ancestral strain boost were essentially equivalent, namely, the BA4/5 bivalent boost was no better than the standard boost. Last night, I heard from Pfizer in a zoom call with Jha and all of HHS (Walensky, Murthy, Kessler and my team at NIH) that in their experiments there was a fourfold higher titer associated with the boost by the bivalent BA4/5 compared to the boost with the ancestral strain. Pfizer claims that their study was controlled whereas the studies by Ho and Barouch were not and the numbers were small. David Ho called me today and emphasized that the combination of numbers of his study and Barouch's study made them equivalent in size to the Pfizer numbers. In addition, he made the important point that there were some discrepancies in the data that were in the press release from Pfizer which did not contain all of the data that made them concerned about the Pfizer data. In addition, David suggested that it is in Peter Mark's interest to agree with Pfizer since Pfizer confirms what his decision was about the BA4/5 bivalent boost. I do not know whether this is David Ho concerned that his data are not holding up or whether he has a very good point that Pfizer is not being totally above board with the presentation of their data. I will have to try to figure this out by discussing it with a few other people. I have already discussed it with Cliff Lane and he thinks that both of those studies don't definitively show the answer since they both have weaknesses. Cliff recommends that the data undergo significant statistical analysis. HOWEVER, Eric Topol reviews the different studies: Bivalent BA.5 Booster Neutralizing Antibody Lab Assessments Suthar 'Shi Pfizer Ho -Barouch "Barouch Bivalent vs. BA.5 Compared to Original 4-fold improved 3-fold improved 4-fold improved Pseudovirus Minimal difference Pseudovirus 1.3-fold increase Pseudovirus No difference LA Times: SINESS COLUMNIST Usa WHO label! Lintage # = US Class Total «= SS %4P I Omicren BAS VOC 32% M247 BO.1,1 YOO 168% 168.7-224% BO. 1 WOOD TRS TILE er BA 4 VOU 985% 6.6-10.5% BF? YOO 0% Fai BAS 2.6 WOO 31% 253% BA 2.75 VOD 20% 128% BA P52 VO> 1.0% O0.8-71.7% BAL 4 VOD OF% O247% BA.1,1 VOD O0% O4h0% B.1.1.429 VOC OFf% O0o00% BA? .12.1 VOC O="F% O000% BAS VOC O0% Oe00% Deita 8.16172 VBM OFf% O0-00% Cther 'thane o.1% 0.040, 1% Bivalent vs. BO.1.1 Compared to Original ~10-fold increased (vs 1 booster) Low, but 3-fold GMT Not assessed Not assessed Not assessed Modest ~1.2-fold increase Great put down of the HELP Report in LA Times: Column: ProPublica and Vanity Fair are pushing the COVID lab-leak theory, but their exposé is a train wreck BY MICHAEL HILTZIKBUSINESS COLUMNIST
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Nov. 5, 2022 I had an amazing evening at the Mohammed Ali Gala in Louisville Kentucky where I received the Mohammed Ali Humanitarian Award for Lifetime Achievement. Others who received similar rewards included Jose Andres and former NBA Rookie of the year. I had a wonderful tour of the Muhammad Ali Museum at the Muhammad Ali Center and I was introduced by Ali's wife Lonnie Ali. I also received a personal tour of the Louisville Slugger baseball bat factory and I was given a bat specifically named for me. And enjoyable time all around. Of note was the extraordinarily enthusiastic reception I received from the people at the Louisville airport and at the Gala event. I was totally mobbed for selfies. Interesting that this is Rand Paul's state (Kentucky) and I thought that I might not be well-received and I actually was totally met with love and admiration. Six other honorees were recognized at Saturday's ceremony for embodying Muhammad Ali's Six core principles: confidence, conviction, dedication, giving, respect and spirituality. Those honorees include: • Confidence Award winner Gitanjali Rao, a 17-year-old from Louisville was named Time Magazine's Kid of the Year for "inventions help to detect lead content in water, provide early diagnosis of prescription opioid addiction, and counter cyberbullying." • Conviction Award winner Lefteris Arapakis from Greece for his work fighting pollution in the Mediterranean Sea. Arapakis also heads up an organization, Enaleia, that teaches people how to clean plastic out of the sea. • Dedication Award winner Mohamad Al Jounde from Syria, has helped give 200 children access to education via the Gharsah School in Lebanon. • Giving Award winner Liam Elkind, a Yale student who co-founded Invisible Hands during the COVID-19 pandemic to help ensure at-risk community members have access to food and medical supplies. • Respect Award winner Malcolm Brogdon, the former NBA Rookie of the year, for his work in Tanzania with the Brogdon Family Foundation, which helps people access clean water and quality education. • Spirituality Award winner Lual Mayen from South Sudan for working for refugee and migrant rights. He also founded Junub Games, an organization that teaches the "importance of peace through video games."
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Nov. 7, 2022 I had a very important meeting today in Jeff Zients' office where he arranged me to meet with Robert Bauer, former lawyer for President Obama and Dana Remus, lawyer for President Biden until July 2022 (4 months ago). Jeff wanted them to advise me about how I should handle my legal counsel for the upcoming oversight hearings that certainly will occur if the GOP take over the house and/or the Senate. It is clear that even with Pro bono considerations Connally whom Brett arrested: ct of Maryland » that this is going to cost me a lot of money since the GOP has promised that they would make my life miserable and blame me for virtually everything that happened bad to the country during the pandemic. Jeff has been an amazing friend to me and the next challenge would be to make sure that I have Secret Service protection after December 31st at which point HHS has stated that they have no responsibility or authority to protect me despite the multiple threats on my life. In addition, HHS will not provide me legal protection after I leave. Later in the day I took off for New York City to receive the Yitzhak Rabin lifetime medical Leadership Award given by American Friends of Rabin Medical Center at the Plaza Hotel. Before I got there it was somewhat of a harrowing experience since I was recognized walking from the Hilton Hotel on 6th Ave and 52nd St to the Plaza Hotel on 59th St and 5th Ave. I was beset by a horde of at least 20 paparazzi who followed me from 6th Ave to 5th Ave walking backwards surrounding me and flashing lights that blinded me. That has never happened to me before and is a full warning of what I'm going to have to expect. I absolutely must have security protection or I am going to be in deep trouble.
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Nov. 8, 2022 Election day! Deaths worldwide down 95% according to WHO RSV surging in USA and also early and touch flu season emerging. PRESS: Cox Media TV;
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2022-11-09 00:00
Anthony S. Fauci
Nov. 9, 2022 Red (GOP) wave did not occur with many (not all) election deniers supported by Trump losing throughout the country. Rand Paul wins in KY and during his acceptance speech says many times that the first thing he is going to do is to Investigate me. However, the Senate may not flip to GOP. Very tough races. Will not know results until December since there is a runoff in Georgia between Warnock (D) and Walker (R). Prepped Erik Stemy for briefing the E & C Oversight Staffers on Wuhan grant PRESS: NPR "Science Friday" with Ira Flatow
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Nov. 10, 2022 Just for the record here is the full story on Connally whom Brett arrested: S. Attorneys » District of Maryland » News SHARE Department of Justice U.S. Attorney's Office District of Maryland FOR IMMEDIATE RELEASE Thursday, August 4, 2022 Man Who Made Threats Against Dr. Anthony Fauci and Other Federal Officials Sentenced to Over Three Years in Federal Prison Greenbelt, Maryland - U.S. District Judge Paula Xinis sentenced Thomas Patrick Connally, Jr., age 57, most recently of Snowshoe, West Virginia to 37 months in federal prison, followed by three years of supervised release, for making threats against a federal official, specifically for sending emails threatening harm to Dr. Anthony Fauci, the current Director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (NIH). Connally further admitted threatening Dr. Francis Collins, the former Director of the NIH, Dr. Rachel Levine, currently the Assistant Secretary for Health at the U.S. Department of Health and Human Services, as well as a Massachusetts public health official and a religious leader. The sentence was announced by United States Attorney for the District of Maryland Erek L. Barron and Deputy Inspector General for Investigations Christian J. Schrank, Office of Inspector General of the U.S. Department of Health and Human Services. "Everyone has the right to disagree, but you do not have the right to threaten a federal official's life," said U.S. Attorney for the District of Maryland, Erek L. Barron. "Threats like these will be prosecuted to the fullest extent of the law." "Today's sentencing shows that individuals threatening violence against federal officials and others will be held accountable for their crimes," said Deputy Inspector General for Investigations Christian J. Schrank of the U.S. Department of Health and Human Services Office of Inspector General. "The public, including public servants, deserve the utmost safety and the assurance that they can perform their duties without interference. Our agency, working closely with our law enforcement partners, will continue to bring those who threaten violence to justice." According to Connally's plea agreement, from December 28, 2020, to July 25, 2021, Connally used an anonymous email account from a provider of secure, encrypted email services based in Switzerland, to send a series of emails to Dr. Anthony Fauci, the current Director of the National Institute of Allergy and Infectious Diseases ("NIAID") and the Chief Medical Advisor to President of the United States, threatening to harm and/or kill Dr. Fauci and members of his family. One of the emails threatened that Dr. Fauci and his family would be "dragged into the street, beaten to death, and set on fire." On April 24, 2021, alone, Connally sent seven threatening emails starting at 10:05 p.m. As detailed in Connally's plea agreement, also on April 24, 2021, beginning at 9:34 p.m., Connally sent Dr. Francis Collins, the then-Director of the NIH, a series of four emails threatening Dr. Collins and his family with physical assault and death if Dr. Collins did not stop speaking about the need for "mandatory" COVID-19 vaccinations. As stated in his plea agreement, Connally admitted that he sent the threats to Drs. Fauci and Collins with the intent to intimidate or interfere with the performance of their official duties and with the intent to retaliate against Dr. Fauci and Dr. Collins for performing their official duties, including discussing COVID-19 and its testing and prevention. Connally also admitted sending emails threatening harm to three other individuals. Specifically, on November 24, 2020, Connally sent a series of six threatening emails to Dr. Rachel Levine, then Secretary of Health for the State of Pennsylvania, at Dr. Levine's email account at the Pennsylvania Department of Health. The subject lines and body of the emails threatened Dr. Levine with physical violence and death. Similarly, on August 31, 2020, Connally sent an email threatening physical violence and death for a public health official in Massachusetts. Finally, on
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Nov. 11, 2022 Exciting day. In preparation for the installing of my "living portrait' by Hugo Crosthwaite into the National Portrait Gallery tomorrow, there was a gala celebration at the home of Jeff Bezos 2330 S Street, NW. His home is an enormous mansion that goes on and on. It was formally a textile museum that he converted to his Washington DC home. The guest list was AAA. Notable conversations well with Jose Andres who wants to cook a special one-on-one dinner with me at his home in DC. Also I had a very serious conversation with Hillary Clinton who said that she thinks about me every day knowing that I will have an experience if the GOP games either chamber of the Congress similar to her experience with Benghazi. She offered to appear with me at the hearings as a physical show of support. I am not so sure that that is a great idea since that might politicize me even more than I've been politicized. I also have a warm conversation with Marian Wright Edelman...and several others. The other awardees (and their presenters) were: Jose Andres (Laurene Powell Jobs), Clive Davis (Alicia Keyes)Ava DuVernay (Isabel Wilkerson), Marian Wright Edelman (Hillary Clinton), Serena Williams (Mellody Hobson) Venus Williams (Sonya Haffey and Isha Price) David Rubenstein will present me. After the gala we were invited to another gala at the Cafe Milano, celebrating their 30th anniversary. I went there out of respect to Franco Nuschese. However, it was somewhat of a stressful experience since I got completely surrounded by "well-wishers" who anted selfies and/or to shake my hands. It was really overwhelming and reminds me why I will need security for some time.
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Nov. 12, 2022 Jeff Zients 56th birthday. I dropped off a signed copy of Harrison's at his house. An historically memorable day at the National Portrait Gallery. A Gala event was held tonight honoring the inductees to the National Portrait Gallery. It was the highest level of AAA list you could imagine in Washington DC. There was a red carpet entry to the gallery which resembled the red carpet entry into the Academy Awards with multiple TV and radio and print interviews as you walk along the red carpet before you get to the main place where photographs were taken. It started off as a very wamt night for November 12 at 75 F and clear sky, but by the end of the night and into tomorrow morning it got much colder. It was very clear that the extraordinary talent and unique approach that Hugo took captivated the audience of more than 750 people at this gala opening and dinner affair. I was the first awardee who was recognized, being introduced by David Rubenstein. I received a prolonged standing ovation from the crowd (as did others). David gave his usual tongue-in-cheek introduction of me telling the story of how he offered me a "higher calling' in private equity 12 years ago. I had wonderful conversation with other awaredees and others who expressed sincere appreciation of what I have done over more than 50 years. Of particular note were conversations with Marian Wright Edelman who called me "her hero and a true national treasure". Also, Jose Andres (he wants to invite me to a private dinner at his home) Clive Davis, Ava DuVernay and Isabel Wilkerson, and Venus Williams (not so much Serena) were very warm towards me. It was an extraordinary affair. In the middle of it, Dan Diamond from the Washington Post texted me that the GOP did not take the Senate and so Rand Paul will not have the opportunity to harass me with senate oversight hearings. We were invited to go across the street by Jose to his restaurant Zaytinya for after hours champagne. He quickly stopped there but Jose had not arrived and so we left a message of greeting to him and took off since it was already 11:50 PM. A truly AMAZING evening!! PRESS: CBS Saturday Morning with Michelle Miller; Der Spiegel article came out (see above);
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Nov. 13, 2022 (Sunday) Mark Dybul texted me to alert me that Mike Gerson was fading quickly and was in Georgetown Hospital waiting for Hospice. Bles Building, 4th Floor, Room 24. It was very sad to see. Mike was in dire straits literally on his last few hours to few days. He recognized me and was obviously very glad to see me. We had a brief conversation I told them how important he was to me and to the rest of the world and he said that he truly appreciated that. A truly great man will soon leave us. Was briefed today by the Moderna team led by Steve Hoge on the latest data of their bivalent BA4/5 boost. The data look really very good and it is clear that the updated booster performs very well and better than the ancestral booster across the board in inducing antibodies against BA 4/5 and all of the sub variants of omicron including BQ.1.1. This is very good news for the upcoming winter. However, there is still very little uptake of this updated booster by the general public. There is this complacency that the pandemic is over and the confusion about why we need to continually get updated boosts because of the combination of appearance of new variants together with the lack of durability of response to either vaccine or infection. Catch up on prior important information. From May, 2020: hy F HHI fa " os *y ol om "yg a fe a, ff x YY XK KX a /Shutterstock All of Jacob Wohl's Spectacularly Failed Smear Attempts