COVID-19 Records

Transcript segment

Baric Transcribed Interview (Redacted), p.14 · baric_ti:utt:00064

Page text: p.14 · original PDF

Date
2026-04-10 09:00 (day precision)
Type
transcript segment · interview
recipient
Ralph S. Baric, Harry Kazenoff, David T. Lambeth III, William Henderson, Clark Ervin, Jake Greenberg
speaker
Christina Salazar
Topics
Vaccines
Did you already have a vaccine developed with them, or was it still --

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Did you already have a vaccine developed with them, or was it still -- needs context speaker_own questions

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  1. 2026-04-10 09:00 Christina Salazar open
    Okay. And so on the 4th you had that call, and then I know that you had a call, I think, with Erik Stemmy on the 7th?
  2. 2026-04-10 09:00 Ralph S. Baric open
    Around the 7th. There were a lot of phone calls in the first three weeks of January. But certainly I did talk to him. The exact date, I'd have to look at my notes. I thought it was more around the 11th or 12th, but it could easily be the 7th.
  3. 2026-04-10 09:00 Christina Salazar open
    Was that the first NIH employee that you had spoken to, or had you spoken with others?
  4. 2026-04-10 09:00 Ralph S. Baric open
    Somewhere around those dates I also talked to Barney Graham at the VRC, because we'd been working since about 2017 on mRNA-LNP-based vaccines using MERS coronavirus as, in essence, a paradigm model for how to develop an effective vaccine against coronavirus.
  5. 2026-04-10 09:00 Christina Salazar
    Did you already have a vaccine developed with them, or was it still --
  6. 2026-04-10 09:00 Ralph S. Baric open
    We had an mRNA vaccine for MERS coronavirus that had been tested in mice, both young and DC.Scheduling@LexitasLegal.com old mice, and it was extremely effective. I think that data was immediately incorporated into the discussions, that I was not part of, but discussions at the Federal level, in terms of prioritizing which vaccines might go forward. So the reason, I think, that we were particularly so excited about that data is that most of the vaccines that I have tested against coronaviruses, epidemic or pandemic, not pandemic, epidemic coronaviruses like the original SARS 2003 strain, or the MERS strain, worked effectively in young animals. But when you took them into aged animals, where the vaccines are less affected by about tenfold, the vaccines would fail. And the beauty about the VRC mRNA vaccine was that the neutralizing titers in the immune responses were as effective in the old animals as the young animals, so they were fully protected. And that was very impressive.
  7. 2026-04-10 09:00 Christina Salazar open
    And so the VRC Moderna vaccine.
  8. 2026-04-10 09:00 Ralph S. Baric open
    Yeah. Moderna certainly was engaged. Whether they actually manufactured the vaccine that was put in the animals or not, or whether NIH made that vaccine and put it in, I don't know.
  9. 2026-04-10 09:00 Christina Salazar open
    And your vaccine, what was it called?

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