Private channel session 922

12 messages over 1h 0m, 2021-02-05 – 2021-02-05.

A “conversation” here is an activity session — a run of messages with under 60 minutes of silence inside it. The channel had no native conversation boundaries.

1. 2021-02-05 00:06 Andrew Rambaut open PDF p.481
   @Eddie Holmes B.1.1.4 + E484K tree: [shared file(s): image.png]
2. 2021-02-05 00:07 Andrew Rambaut open PDF p.481
   So a recent cluster (presumably one at the top is an independent instance).
3. 2021-02-05 00:09 Edward C. Holmes open PDF p.481
   Thanks! So, a recent cluster of B.1.1.4 that have independently acquired EriK? Perhaps from the US?
4. 2021-02-05 00:13 Edward C. Holmes open PDF p.481
   Sorry, now seen your email! Thanks!!
5. 2021-02-05 00:17 Andrew Rambaut open PDF p.482
   Spike mutations: D614G, E484K, G769V, W152L
6. 2021-02-05 00:18 Andrew Rambaut open PDF p.482
   We are currently looking at whether 484K is starting to appear more frequently (in multiple backgrounds) than it did before or whether we just have more cases and more sequencing.
7. 2021-02-05 00:20 Edward C. Holmes open PDF p.482
   Yes, very interesting question. That we are seeing it in Australia is perhaps tell-tale.
8. 2021-02-05 00:20 Andrew Rambaut open PDF p.482
   For your case I would say it is irrelevant with respect to action that it is a recent cluster - just that it has 484K. I.e., itis not a 'cluster of concern' but it has a mutation of concern.
9. 2021-02-05 00:21 Andrew Rambaut open PDF p.482
   If you look at the number of States that cluster spans - it does suggest widespread transmission in the US.
10. 2021-02-05 00:21 Andrew Rambaut open PDF p.482
    But everything has been spreading like crazy in the US
11. 2021-02-05 00:23 Edward C. Holmes open PDF p.482
    I think the local health people just like to be doing stuff. Hopefully this person gets put in a room at the end of thecorridor.
12. 2021-02-05 01:07 Edward C. Holmes open PDF p.482
    The quantum computer sequencing sounds interesting. I might link him up with EgoHealth :zany_face: [shared file(s): Screen Shot 2021-02-05 at 8.03.49 pm.png]