Slack / Private Message Drop — page 977

[2021-07-08 00:39:23] [Andrew Rambaut] That is bonkers - totally going for cold-chain origins. They are going to love the Italian Jobbie. [2021-07-08 01:21:33] [Eddie Holmes] Oh yes. I really want to see that online. [2021-07-09 01:21:15] [Eddie Holmes] This is going to ruffle a few feathers: https://profilebooks.com/work/spike/ [2021-07-09 01:48:00] [Andrew Rambaut] Love the name [2021-07-09 03:00:12] [Andrew Rambaut] Question from Jon Cohen: [2021-07-09 03:00:12] [Andrew Rambaut] ```Is this accurate? How likely is is that humans infected civets with SARS-CoV? Begin forwarded message: From: Frutos > Date: July 8, 2021 at 8:06:23 PM PDT To: Jon Cohen > Subject: Re: Interesting question [EXTERNAL EMAIL] In the trees SARS-CoV RdRp and spike are shown in red. The host code is Plar for civets and Hsap for humans. None is ancestral to the other. It is the same virus. Le 09/07/2021 à 04:19, Jon Cohen a écrit : So you disagree with the rooting that shows civet SARS-CoV is ancestral to human? On Jul 8, 2021, at 6:31 PM, Frutos .fr> wrote: [EXTERNAL EMAIL] I didn't fully answered. Yes it is misguided because of quasispecies and metapopulation but also because of the flawed idea of a linear process. That it goes from A to b to C to D in a linear way. No. It is a non linear process. The circulation works the same for SARS as for COVID. Civets have been contaminated by humans not the other way around. Like minks with SARS-CoV-2. Le 09/07/2021 à 03:00, Jon Cohen a écrit :