Slack / Private Message Drop — page 207

the 'pre-circulation' hypothesis of a furin site-lacking virus in humans a little more (or other animals - maybe cat-like?). It then picks up that site - which is seen in other human coronaviruses - and boom. Pandemic. Interestingly, the exact site in SARS2 is observed in some of the FIP isolates, hence a potential connection to cat-like animals. Good thread summarizing some of the findings: https://twitter.com/influenzal/status/1311959153166954498?s=20 [and of course - I want to know if they virus lacking the furin site can actually pick it up after repeated passage in culture on e.g., human lung cells... :wink: ] [2020-10-02 10:03:12] [Robert Garry] also with the cats! [2020-10-02 10:04:02] [Kristian Andersen] Yes [2020-10-02 10:04:59] [Kristian Andersen] Interestingly - I'm on a call with all the San Diego clinical labs at the moment. Everybody is like "WTF with those Tweets/timing last night given that the house is full of rapid tests...." [2020-10-02 10:37:15] [Robert Garry] Maybe pass the virus on cat cells. [2020-10-02 10:38:18] [Kristian Andersen] Yes - or human lung tissue cells. Bob, we need you to do this... :wink: [2020-10-02 13:05:07] [Robert Garry] On it. [2020-10-02 13:06:42] [Robert Garry] Meanwhile some possible clues to the transmission https://www.southbendtribune.com/news/local/notre-dame-presi dent-tests-positive-for-covid-19/article_ba3ac3dc-04ce-11eb-9204-ff90cfd4d130.html They better damn well get some sequences. Mike Lee Senator also positive not sure how he fits in. [2020-10-02 13:14:10] [Kristian Andersen] Yeah, a bunch of people testing positive - clearly a SSE over the weekend. And clearly real, not fake - so good call Bob! I'll remember to sleep before putting on my tinfoil hat next time... (yet, this is Trump, so we unfortunately _always_ have to consider BS a very likely possibility). As for Trump himself - well, you reap what you sow. I don't want anybody to get COVID-19 - including Trump - but he's the number one reason why it's so widespread. I have no sympathy for him - I reserve that for the other 50k people testing positive every single day and the families of the 200k+ people now dead from COVID-19 in this country. [2020-10-02 13:16:19] [Kristian Andersen] Adding up... https://twitter.com/oliverdarcy/status/1312115176984903680?s=20 I'm sorry, but this is just idiotic - and so predictable (and, most importantly, preventable). Joe better not have the