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BACKGROUND INFORMATION HHS/White House Medical Countermeasure Initiative (MCM) Briefing Friday, April 16, 2010 9:00 am - 10:00 am ACTION REQUIRED BY THE DIRECTOR: None PURPOSE OF MEETING: The purpose of the meeting is to brief you on NIAID's role in the HHS/White House Medical Countermeasure (MCM) Initiative. BACKGROUND: NIAID has participated in weekly meetings with The White House (National Security Staff - NSS) and HHS staff to create a "transforming" initiative on how the US government responds to deliberate and naturally occurring biological threats through the development of medical countermeasures (MCM). NSS Staff will soon seek new money from OMB to support this new initiative. The "Program" includes 4 elements: 1) boosting regulatory science; 2) developing Transformational Centers of Excellence for Advanced Development and Manufacturing of MCM; 3) establishing an independent strategic investment firm (i.e. a government venture capital-like organization) for innovation in MCM; 4) the development of a "concept exploitation focus" to help stimulate discovery and translation. PARTICIPANTS: Anthony S. Fauci, MD, Director, NIAID Michael G Kurilla, MD-PhD Director, Office of BioDefense Research Affairs Associate Director for BioDefense Product Development , NIAID DISCUSSION POINTS/TALKING POINTS (using concise/to the point bullets): Attachments: • Bios • Relevant correspondence • Supplemental Information • Etc. Thank you, Nicholas DiCrosta Management Intern currently on rotation with the NIH Executive Secretariat

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Meeting Material request -- 4/16 Briefing with Dr. A. Fauci, Dr. M. Kurilla and Dr. Patterson re: MCM Good afternoon Ms. Conrad, Are there further materials you and Dr. Fauci will be submitting to the ES in regard to this meeting? If so, please use the attached template and return to me at your earliest convenience. Thank you! Nick DiCrosta Management Intern, Class of 2011 Currently on rotation with the NIH Executive Secretariat (p) mail.nih.gov Good afternoon Ms. Conrad As you know, Dr. Collins will be meeting with Dr. Fauci regarding Medical Countermeasures. You have been assigned the lead in preparing briefing information for this meeting. Please prepare the material for this meeting using the outline below and submit this material electronically to me as soon as possible. BACKGROUND INFORMATION Name of Meeting Date of Meeting Time ACTION REQUIRED BY THE DIRECTOR: PURPOSE OF MEETING (one sentence): BACKGROUND (short summary, 3-4 sentences): PARTICIPANTS: DISCUSSION POINTS/TALKING POINTS (using concise/to the point bullets): 2010-04-14 email 487–490