Gates Package — page 80

Cc: Koup, Richard (NIH/VRC) [E] Subject: Re: Support on Ebola Tony, Several relevant items. 1. We heard from GSK that Welcome trust is willing to help support expanded international trials and this is being pursued. Rip Ballou of GSK is coordinating with Rick Koup. 2. We discussed with Nelson Michael and colleagues yesterday, a trial in Uganda that would be run by African investigators and generate data in African volunteers. Some funding to support this may be helpful., but there may be existing NIAID/DoD funds existing to support this. 3. GSK is close to final decision about making larger lot of vaccine. BARDA or Gates funding could play a role here. There are many moving parts here and several fairly imminent decisions. Rick has been on all the calls with BARDA, GSK, WHO etc. A first key step in to find out what BARDA plans to do, and based on that, decide if there are other funding gaps. Rick, do you know when we will hear specifically what BARDA will fund, how much and when this will be announced. Will they support some GSK manufacturing activities? John Apple iPad On Aug 7, 2014, at 9:50 PM, "Fauci, Anthony (NIH/NIAID) [€]" <{@ niaid.nih.gov> wrote: John: See e-mail string below. Is there any way that you can think of where Gates can be of assistance to us in the ChimpAd Ebola vaccine development? Tony From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, August 07, 2014 9:49 PM To: Collins, Francis (NIH/OD) [E] Subject: RE: Support on Ebola I have allocated enough money to do the VRC vaccine trial and so we do not need Gates money. I believe that BARDA has enough money to accelerate the zMapp production. I will give John Mascola a call and find out if he can think of any way that Gates can help with his trial. From: Collins, Francis (NIH/OD) [E] Sent: Thursday, August 07, 2014 9:20 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: RE: Support on Ebola I was thinking exactly the same thing. Do you see ways that BMGF could be helpful? FC From: Fauci, Anthony (NIH/NIAID) [E] Sent: Thursday, August 07, 2014 7:37 PM