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Gates Package — page 36

of 1375 pages

← p.35 p.37 → · this page in the original PDF · package

Favipiravir PK, Additional Considerations Liver impairment * Child-Pugh (5-6): 1.7 to 2.3 fold increase AUC,., * Child-Pugh (7-9): 1.7 to 2.1 fold increase AUC,., ¢ Child-Pugh (10-15): 2.3 to 4.5 fold increase AUC,,; Body Weight Body wt vs. Gender, 2400 mg Favipiravir Single Dose (JP105) 10007015 OCT 15, 2014 Confidential

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gates:exh:00024 attachment 36