Tony's Diary Package — page 667

Total Sample Total Endpoints Efficacy '9,800,000/543,000 All Endpoints "Severe" Infections Doses Astra Zeneca J&J Pfizer Moderna Novavax Sputnik Z 32,449 (2:1, V:P) 43,783 43,355 28,207 14,040 21,977 (3:1, V:P) 76% 72%* 95% 95% 90%* 91% Vaccine NA Placebo NA Vaccine 116 Placebo 348 Vaccine 8 Placebo 162 Vaccine 11 Placebo 225 Vaccine 10 Placebo 96 Vaccine 16 Placebo 62 Vaccine 0 Placebo 8 Vaccine 5 Placebo 34 Vaccine 1 Placebo 3+ Vaccine 1 Placebo 29 Vaccine 0 Placebo 5 Vaccine 0 Placebo 20 For ancestral, D614G strain; NA-not available; Novavax efficacy 96% ancestral (1 vs 28 endpoints); 86% B.1.1.7 (8 vs 58 endpoints) * For Pfizer, 9 placebo vs 1 vaccine after 1** dose (3 vs 1 in planned efficacy analysis) March 25, 2021 - Global - 124,200,000/2,700,000; USA - 29,800,000/543,000 After a Zoom meeting yesterday with the DSMB Chaired by Rich Whitley, it became clear that they are furious with AZ since they feel that the AZ people are "pathological liars". It is a shame, because their vaccine is really a good vaccine; however, with their dishonest actions, they are casting discredit on the vaccine. Continues to plateau amid concerns for surge. Spring break is at hand. Variants in the USA: