Tony's Diary Package — page 645

Company Platlonm a Non-clinical results f who got Fs vaccine MANA T 2 FS Neutralizing Abs: Strong I "15,000 mRNA in lipid Thi CD44, CDB«: moderna nanoparticle protection from challenge (macaques) BNTI62b2 Z Neutralizing Abs; Strong I ~18,000 eS Pfizer mRNA in lipid Thi CD44, CD8+: nanoparticle protection from challenge (macaques) JNJ-78436725 Neutralizing Abs; Strong I "22,000 === Non-replicating Thi CD4+ > Th?; (Da; US, Latin human challenge protection America, adenovirus/ DNA [macaque] 5. Alrica AZD 1222 Z Neutralizing Abs; Strong I "8588 Non-replicating Thi CD44 > Th?: Cbd: Astrazeneca I Chimp Adenovirus- protection fram DNA challenge (macaques) NVX-Cov2a73 Neutralizing Abs; Strong I "9700 NOVAVAX, spike protein/RBD + Thi CD4 > Th2; challenge I (Phase 3 Matrix M adjuvant protection (macaques) WK: 2b SA) Ad26 and Ad5 MAbs; IFIN-y secretion ~14964 Sputnik v adenovirus/ONA PMBCs, cellular response S cinavar' I Inactivated virus Antibodies (T cells next) I 12500 ds ',800,000/523,000 Protection from COVID severe dz [some at home) Protection fram hospitalization from COVID-19 Efficacy against milder COVID '5800,000/524,000 97% (30 cases in 94.1% alter #nd placebo arm: O in dose vaccine reported but hospitalized] 1 severe per FDA) 100% (9 cases in 95% Placebo arm; 0 in vaccine- 1 initially severe but not) 85.4% acrass 3 sites I 727% U5: 68% (7 deaths, 16 Latin America; hospitalizations, all! I 64% 5. Africa placebo arm) (96% B1.351) 100% (15 in placebo I 70% overall: = all hospitalized: 0 76% 1 dase: 5. in vaccine) Africa trial halted for mild 100% (but only 1 96%; 89% B11? severe in placebo; 0 I UK; 60% 54 in vaccine) (94% B.1.351) 100% (20 in placebo; I 91.6% 0 vaccine) 82% (tz needed) 50.7% across GOP at the local level are trying to pass laws that suppress minority voters such as saying that you cannot give food to people who are waiting in line for hours to vote. This disproportionately affects African American voters. PRESS: MSNBC with Tiffany Cross; March 7, 2021 - Global - 116,100,000/2,600,000; USA - 28,800,000/523,000 Status of vaccines in USA from Monica Ghandi: The intensity of both my popularity and of the hate that the far right have of me increases: Fauci.pdf PRESS: CBS "Face the Nation" with Margaret Brennan March 8, 2021 - Global 116,500,000/2,600,000; USA - 28,800,000/524,000 Plateau starting to come down"