Tony's Diary Package — page 1051

Pluses Minuses First updated vaccine since 2020 No BA.5 variant specific human neutralizing antibody data Matches current BA.5 wave and current related variants (BA.4.6) Unknown if it will have better clinical outcomes than original booster Made at scale in ~2 months, fulfilling mRNA platform promise May add to booster hesitancy, lack of uptake, only 32% of population Relies on flu vaccine updating strategy from mice data used for decades SARS-CoV-2 is not influenza Prior human data for immune response to BA.1 and Beta variants Potential of imprinting to diminish effect, would BA.5 monovalent vaccine be better? Shows agility of FDA Lack of input by VRBPAC Potential to lessen infections and transmission May not impact infections and transmission reading whole article): Recent article in Salon (worthwhile reading whole article): COMMENTARY Farewell Dr. Fauci: How the right turned a national hero into a villain in service of Donald Trump The right's attack on science is the most dangerous of its cynical power plays. Fauci is just collateral damage By HEATHER DIGBY PARTON Columnist Nice cartoon from 2020 by Mark Tatulli :