Diary Prequel Package — page 439

PM CT in blood is negative (40 CT) Also, urine, saliva is negative. Interesting issue is that axillary sweat is persistently positive (~32 CT). Cliff and I will meet with the US Ambassador to Guinea at the State department tomorrow to try and work out the issue with performing an RCT vaccine trial in Guinea. Marie-Paule Kieny is truly a fraud and acting purely on political motives. The WHO does not want us or anyone to start an RCT in Sierra Leone with ZMapp until they finish their TKM-EBOV open access trial (treat one ETU) and compare it historically to another ETU. This stance even though the pre-clinical data on ZMapp are infinitely more promising than those from TKM-EBOV. They would rather finish their study and delay the start of a trial with a promising drug just because they "politically" want to be a player. Also, in the vein of everybody wants to be somebody, various groups including Welcome Trust, and even the BMGF want to start the Global Research Collaboration for Infectious Diseases Preparedness (GloPID-R) - a network of funding organizations in the area of infectious Diseases research. Obviously, we are the major player and these other organizations have little to ad, but they want a network that would require us to go to endless meetings and give them a say of what the direction of the research would be. Ugh! Been there, done that with the HIV Vaccine Enterprise, etc. March 31, 2015 - continues to improve with increased strength. Need to figure out way to get him back to Dallas where his parents live. He lives in Houston. Technically, since he is now PCR negative X2, he can fly commercial; however, the optics will be bad - people get hysterical if they find out he is an ex-Ebola patient. And so wrote to Paul Farmer to see if PIH will pay for a charter for him to fly from DC to Dallas. Cliff and I went down to State Department to meet with US Ambassador to Guinea - Alexander Mark Laskaris to get his help in smoothing the way for us to do the RCT for the Ebola vaccine in Guinea since Guinea is where the infections are and the Norwegians and WHO clearly do not want us to do the trial there (see above). Laskaris totally gets that WHO are the "bad" guys and have lost all credibilityand he will support us. Chris and I took out Denise and jack to Fiola Mare restaurant in Georgetown for jack's 80th birthday. Below is final communication between Harold Varmus in his last official day as NCI Director and me. He has been a dear friend as NIH Director and over the past 5 years as NCI Director: From: Varmus, Harold (NIH/NCI) [E] Sent: Tuesday, March 31, 2015 3:51 PM To: Fauci, Anthony (NIH/NIAID) [E] Subject: Re: Nice article