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UPDATE ON NEWLY DISCOVERED CORONAVIR Ee ee Virion Structure Enveloped RNA virus Enveloped RNA virus En Outbreak period 2003-2004 2012-present Initial site of isolation Guangdong province, China Saudi Arabia No. of countries/cases No. of cases (mortality) 8,096 (9.6%) 2,494 (~34%) No. of cases U.S. 2 (2014) Reservoir (intermediate host) Incubation period Infectivity, rho Super spreaders Asymptomatic/mild Spread Attack Rate Transmission (including to HCP) Treatment (PEP) Infection Prevention* *likely higher than SARS-CoV Bats (palm civet) 2-7 days (range, 2-21) 1.8-3.0 Yes No 10.3% to 60% Droplet/Direct, Airborne/Indirect? Supportive (none) Airborne, contact, face shield Bats (dromedary camels) 2-7 (range, 2-14 days) 0.3-1.3 Yes (uncommon) Rare 4 to 20% Droplet/Direct, Airborne/Indirect? Supportive (none) Airborne, contact, face shield Bat 2-14 day U Yes (1 ?, A S Airbor Ro>3.0 basically need to reduce reproductive rate by >75% to s