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@ Preliminary DEVELOP ORAL BIOLOGICS WHAT ARE ULTRA LOW-COST BIOLOGICS (OR FOOD-GROWN ANTIBODIES)? Solving immune deficiencies What will this contain? Potential platforms Deficient Colostrum coer eee Supplement KEY QUESTION(S) the gut such that they are stable, active, and durable? How do we produce and deliver biologics into Adaptive immunity Innate immunity Human milk oligosaccharides Microbiome, cytokines, etc. of gut-directed interventions Scalable platform that allows for production WHAT POTENTIAL RELATIONSHIPS COULD ACCELERATE THIS WORK? Be 26 . BACTOLIFE "MassBio WYENTAUA kueanss 'Tufts UNIVERSITY And more, including new companies POSSIBLE APPLICATION(S) Synthetic colostrum as a supplement to improve gut health of infants and children Not for distribution' 6