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Terms, acronyms, and abbreviations Antibodies: Proteins created by the immune system that grab onto the surface of a virus, bacterium, or parasite and attempt to neutralize it. Breakthrough case: an infection that occurs in a person who has been vaccinated against the disease. Breakthrough cases may eventually be prevented by transmission blockers. CEPI: the Coalition for Epidemic Preparedness Innovations, a non-profit created in 2017 to accelerate work on vaccines against new infectious diseases and help those vaccines reach people in the poorest countries. Gavi, the Vaccine Fund: a non-profit created in 2000 to encourage manufacturers to lower vaccine prices for the poorest countries in return for long-term, high-volume and predictable demand from those countries. Formerly known as the Global Alliance for Vaccines and Immunization. Genome, genomic sequencing: The genome is the genetic code of a specific organism. All living things have genomes, and every genome is unique. Sequencing an organism's genome is the process of figuring out the order in which the genetic information appears. Global Fund: officially the Global Fund to Fight AIDS, TB, and Malaria, a non-profit partnership designed to end the epidemics of those three diseases. IHME: the Institute for Health Metrics and Evaluation, a research organization based at the University of Washington that develops evidence to guide decisions about public health.