Attachment

First large-scale trial to investigate whether home use of cookstoves that run on LPG improve air quality sufficiently to offer measurable health benefits. o Enrollment began February 1, 2018. o Increased BMGF interest in endpoint of severe pneumonia confirmed by the study team with consolidations in the lungs and/or hypoxemia is leading to potential new designs, including proceeding with the trial as initially proposed, and in parallel, developing local pneumonia surveillance systems in the same localities.